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BENZİL BENZOAT (BENZIL BENZOAT)

Formül: C6H5CH2OOCC6H5
INCI: Benzil benzoat
CAS No: 120-51-4
EINECS No: 204-402-9
Benzil benzoat, benzoik asidin benzil alkol ile biçimsel olarak yoğunlaştırılmasıyla elde edilen bir benzoat esteridir. Polyalthia cinsinin bitki türlerinden izole edilmiştir. Bir scabicide, bir akarisit ve bir bitki metaboliti olarak rol oynar.
Bir benzil ester ve bir benzoat esterdir. Benzoik asitten türemiştir.

Üretim
Benzil benzoat endüstriyel olarak sodyum benzoatın bir baz varlığında benzil alkol ile reaksiyonu veya metil benzoat ve benzil alkolün karşılıklı esterlenmesi yoluyla üretilir.
Toluen oksidasyonu ile benzoik asit sentezinin bir yan ürünüdür. Katalizör olarak sodyum benzilatla (sodyum ve benzil alkolden üretilen) benzaldehit kullanılarak Tishchenko reaksiyonu ile de sentezlenebilir.

UYGULAMALAR: Benzil Benzoat ilaçların sentezinde (özellikle skabisit olarak antispazmodik ilaçlarda ve pedikülozu tedavi etmek için) kullanılır.
Benzil benzoat kokuda uygulama bulur. Ön fiksaj ajanı olarak kullanılır. Benzil benzoatın kendisi aktif bir koku bileşeni değildir.
Ana bileşenlerin kararlılığını ve koku özelliklerini geliştirir. Mitisit olarak ve gıda alanında kullanılır. Ayrıca polimerler ve selüloz için plastikleştirici olarak kullanılır.

Benzil benzoat, ilaç ve böcek kovucu olarak kullanılan organik bir bileşiktir. İlaç olarak uyuz ve biti tedavi etmek için kullanılır.
Uyuz için, permetrin veya malathion tipik olarak tercih edilir. Cilde losyon olarak sürülür. Tipik olarak iki ila üç uygulama gereklidir.
Peru Balsamı, Tolu balsamı ve bir dizi çiçekte de bulunur.

Yan etkiler ciltte tahriş olabilir. Çocuklarda tavsiye edilmez. Diğer hayvanlarda da kullanılır; ancak kediler için zehirli olduğu düşünülmektedir. Nasıl çalıştığı belli değil.

Benzil benzoat ilk olarak 1918'de tıbbi olarak incelenmiştir. Dünya Sağlık Örgütü'nün Temel İlaçlar Listesi'nde yer almaktadır. Benzil benzoat, diğerleri arasında Scabanca markası altında satılmaktadır ve jenerik bir ilaç olarak mevcuttur.
Amerika Birleşik Devletleri'nde tıbbi kullanım için mevcut değildir.


Diğer isimler: benzoik asit fenilmetil ester, benzil alkol benzoik ester; CAS Numarası: 120-51-4

Tıbbi
Benzil benzoat, insan uyuzları için etkili ve ucuz bir topikal tedavidir. Vazodilatatör ve spazmolitik etkileri vardır ve birçok astım ve boğmaca ilacında bulunur.
Hipogonadizmi tedavi etmek için bazı testosteron replasman ilaçlarında (Nebido gibi) eksipiyan olarak da kullanılır.

Benzil benzoat, veterinerlik hastanelerinde topikal bir akarisit, kabuk öldürücü ve pedikülisit olarak kullanılır.

Tıbbi olmayan
Benzil benzoat, chiggers, keneler ve sivrisinekler için bir kovucu olarak kullanılır. Parfüm endüstrisinde boya taşıyıcı, selüloz türevleri için çözücü, plastikleştirici ve sabitleyici olarak da kullanılır.

Yan etkiler
Benzil benzoat, laboratuvar hayvanlarında düşük akut toksisiteye sahiptir. Hızla benzoik asit ve benzil alkole hidrolize olur. Benzil alkol daha sonra benzoik aside metabolize edilir.
Benzoik asit konjugatları (hippurik asit ve benzoik asidin glukuronidi) idrarda hızla elimine edilir.
Benzil benzoat, laboratuar hayvanlarına yüksek dozlarda verildiğinde aşırı uyarılma, koordinasyon kaybı, ataksi, konvülsiyonlar ve solunum felcine neden olabilir.

Benzil benzoat, topikal bir skabisit olarak kullanıldığında cildi tahriş edebilir. Doz aşımı kabarcıklara neden olabilir ve kurdeşen veya alerjik reaksiyon olarak kızarıklık meydana gelebilir.

Bazı testosteron replasman enjekte edilebilir ilaçlarda bir eksipiyan olarak, benzil benzoat, Avustralya'daki bir vakada anafilaksi nedeni olarak rapor edilmiştir.
Bayer, bu raporu sağlık uzmanlarına yönelik bilgilere dahil etmekte ve hekimlerin bu tür preparatlara karşı "ciddi alerjik reaksiyon potansiyelinin farkında olmaları" gerektiğini önermektedir.
Avustralya'da, Terapötik Ürünler İdaresi için advers ilaç reaksiyonları raporlarını değerlendiren ADRAC raporları, 2011'den beri anafilaksi vakasından bu yana birçok alerjik sorun raporunu göstermektedir.

Kimya
C6H5CH2O2CC6H5 formülüne sahip organik bir bileşiktir. Benzil alkol ve benzoik asidin esteridir. Viskoz bir sıvı veya katı pullar oluşturur ve zayıf, tatlı balzamik bir kokuya sahiptir.
Birkaç çiçekte (örn. Sümbül, sümbül) oluşur ve Peru Balsamı ve Tolu balzamının bir bileşenidir.


Benzil benzoat
Moleküler Formül: C14H12O2
Ortalama kütle: 212.244 Da

CAS NUMARASI. 120-51-4
BENZİL BENZOAT

EINECS NO.:204-402-9
FORMÜL: C6H5CO2CH2C6H5
MOL WT: 212,25
H.S. KODU: 2916.31

 

TOKSİSİTE: Oral sıçan LD50: 1700 mg / kg
SENONİMLER: Benzoik asit fenilmetil ester; Benylate; Ascabin, Scabagen; Vanzoate; Benzyl Phenylformate; Benzil Benzen Karboksilat; Benzil Alkol Benzoik Ester; Ascabiol; Benzoik Asit Benzil Ester; Benzoato De Bencilo;





FİZİKSEL VE ​​KİMYASAL ÖZELLİKLER

FİZİKSEL DURUM: Sıcaklığa bağlı olarak renksiz yağlı sıvı veya broşürler
ERİTME NOKTASI: 17 C
KAYNATMA NOKTASI: 323 C
SPESİFİK AĞIRLIK: 1.118 - 1.122
SUDA ÇÖZÜNÜRLÜK: Çözünmez
KARARLILIK: Sıradan koşullar altında kararlı
UYGULAMALAR: Benzil Benzoat ilaçların sentezinde (özellikle skabisit olarak antispazmodik ilaçlarda ve pedikülozu tedavi etmek için) kullanılır.
Benzil benzoat kokuda uygulama bulur. Ön fiksaj ajanı olarak kullanılır. Benzil benzoatın kendisi aktif bir koku bileşeni değildir.
Ana bileşenlerin kararlılığını ve koku özelliklerini geliştirir. Mitisit olarak ve gıda alanında kullanılır. Ayrıca polimerler ve selüloz için plastikleştirici olarak kullanılır.
CAS No. 120-51-4
Lezzet / Koku Notları: Neredeyse kokusuz
TİPİK ÖZELLİKLER
Deney USP / EP (titrasyon):% 99.0-100.5 fenil metil benzoat; FCC (GC): minimum% 99.0
Koku: Neredeyse kokusuz
Renk: Renksiz
Görünüm: Berrak sıvı
Parlama Noktası: 148 ° C (298 ° F)
Kırılma İndeksi (20 ° C): 1.568 - 1.570
Yoğunluk (20 ° C) (g / ml): 1.118 - 1.122
Özgül Ağırlık (25 ° C): 1.116 - 1.120
Katılaşma Noktası: 18 - 21 ° C (64 - 70 ° F)
Asit Değeri (mgKOH / g): 1.0 maksimum

BENZYL BENZOATE
120-51-4
Ascabiol
Benzoic acid, phenylmethyl ester
Benzoic acid benzyl ester
Benzyl phenylformate
Phenylmethyl benzoate
Benzoic acid, benzyl ester
Benzylets
Benzyl benzenecarboxylate
benzylbenzoate
Antiscabiosum
Benzyl alcohol benzoic ester
Peruscabina
Spasmodin
Venzonate
Benzylis benzoas
Benzylum benzoicum
Benzylester kyseliny benzoove
Benzoesaeurebenzylester
BENZOIC ACID PHENYLMETHYLESTER
Caswell No. 082
Benzylbenzenecarboxylate
EINECS 204-402-9
Benzylester kyseliny benzoove [Czech]
Benzyl benzoate, 99+%
Venzoate
BZM
CAS-120-51-4
benzylbenzoat
Benzyl benzoate [USP:JAN]
Benzyl benzoate [USAN:JAN]
Benzyl Benzoate.
benzoic acid benzyl
BENZYL BENZOATE BP98
BENZOIC ACID,BENZYL ESTER
Benzyl benzoate, >=99%, FCC, FG
Benzyl benzoate, for synthesis, 99.0%
Benzyl benzoate, natural, >=99%, FCC, FG
Benzoic acid-benzyl ester 
Benzoic acid benzyl ester; Benzoic acid phenylmethyl ester



Bensüülbensoaat (et)
bentsyylibentsoaatti (fi)
benzil benzoat (sl)
benzil-benzoat (hr)
benzil-benzoát (hu)
benzilbenzenkarboksilatas (benzilbenzoatas) (lt)
benzilbenzoāts (lv)
benzile benzoato (it)
benzoat de benzil (ro)
benzoate de benzyle (fr)
benzoato de bencilo (es)
benzoato de benzilo (pt)
benzoesan benzylu (pl)
benzyl-benzoát (cs)
benzyl-benzoát (sk)
benzylbenzoaat (nl)
benzylbenzoat (da)
Benzylbenzoat (de)
benzylbenzoat (no)
benzylbenzoat (sv)
benżoat tal-benżil (mt)
βενζοϊκό βενζύλιο (el)
бензил бензоат (bg)

CAS names
Benzoic acid, phenylmethyl ester
IUPAC names
Benzil-benzoát
benzoic acid phenyl methyl ester
Benzoic acid, benzylester
BENZOIC ACID, PHENYL METHYL ESTER
Benzoic acid, phenylmethyl ester
Registration dossier
benzyl benxoate
BENZYL BENZOATE
Benzyl benzoate; Phenylmethyl benzoate
benzyl-2-methyl-hydroxybutyrate dehydrogenase
benzylbenzoate
phenylmethyl benzoate





120-51-4 [RN]
204-402-9 [EINECS]
2049280 [Beilstein]
2138
Benzoate de benzyle [French] [ACD/IUPAC Name]
benzoic acid benzyl ester
benzoic acid, benzyl ester
Benzoic acid, phenylmethyl ester [ACD/Index Name]
Benzyl benzoate [ACD/IUPAC Name] [Wiki]
Benzylbenzoat [German]
Benzyl-benzoat [German] [ACD/IUPAC Name]
Benzylis benzoas
DG4200000
MFCD00003075 [MDL number]
N863NB338G
phenylmethyl benzoate
[120-51-4]
347840-01-1 [RN]
352431-26-6 [RN]
4-09-00-00307 (Beilstein Handbook Reference) [Beilstein]
613-62-7 [RN]
Acarilbial
Acarilbial (Trade name)
Acaril-S
Acaril-S (Trade name)
Acaril-S; Acarilbial; Acarsan; Acil; Antiscabiosum; Antiscabiosum für Kinder; Ascabiol; Ascalol; B.B. Lotion; BE BO; Benzalcor; Benzilbenzoat; Benzogal; Benzotal; Bezo; Finsarna; Gensarna; Miticocan; Novoscabin; Opele; Pharcobenzyl; Sanasar; Saniscabis; Scabicon; Scabiex; Scabin; Scabisol; Scabitox; Tekoce; Zilaben
Acarobenzyl
Acarobenzyl; Benylate; Benzevan; Benzoate de benzyle; Benzoes??urebenzylester; Benzoic acid phenylmethylester; Benzoic acid, benzyl ester; Benzoic acid, phenylmethyl ester; Benzyl benzoat; Benzylis benzoas; Phenylmethyl benzoate
Acarobenzyl; Benzevan; Benzoate de benzyle; Benzoesäurebenzylester; Benzyl benzoat; Benzylis benzoas; Phenylmethyl benzoate; Spasmodine
Acarsan
Acarsan (Trade name)
Acil
Acil (Trade name)
Antiscabiosum
Antiscabiosum (Trade name)
Antiscabiosum für Kinder
Antiscabiosum für Kinder (Trade name)
Ascabin
Ascabiol
Ascabiol (Trade name)
Ascalol
Ascalol (Trade name)
B.B. Lotion
B.B. Lotion (Trade name)
BE BO
BE BO (Trade name)
Benylate [Trade name]
Benylate (TN)
Benzalcor
Benzalcor (Trade name)
Benzevan
Benzilbenzoat
Benzilbenzoat (Trade name)
Benzoate de benzyle [ACD/IUPAC Name]
Benzoes??urebenzylester
Benzoesaeurebenzylester
Benzoesäurebenzylester
Benzogal
Benzogal (Trade name)
benzoic acid phenylmethyl ester
BENZOIC ACID PHENYLMETHYLESTER
BENZOIC ACID,BENZYL ESTER
Benzoic acid-benzyl ester
Benzotal (Trade name)
Benzyl 2-naphthyl ether
Benzyl alcohol benzoic ester
Benzyl benzenecarboxylate
Benzyl benzoat
Benzyl benzoate (JP15/USP) [USP]
Benzyl benzoate (natural)
Benzyl benzoate [USAN:JAN]
benzyl benzoate 99%
BENZYL BENZOATE BP98
benzyl benzoate, 99+%
Benzyl benzoate, BP, Ph. Eur. grade
Benzyl benzoate, USP grade
Benzyl Benzoate-d12
Benzyl phenylformate
Benzylbenzenecarboxylate
benzylbenzoate
benzyl-benzoate
Benzyl-d5 Benzoate
Benzylester kyseliny benzoove
Benzylester kyseliny benzoove [Czech]
Benzylets
Benzylum benzoicum
Bezo
Bezo (Trade name)
BZM
Colebenz
EINECS 204-402-9
Finsarna
Finsarna (Trade name)
Gensarna
Gensarna (Trade name)
Mange Treatment
Miticocan
Miticocan (Trade name)
Novoscabin
Novoscabin (Trade name)
Opele
Opele (Trade name)
Peruscabin
Peruscabina
Pharcobenzyl
Pharcobenzyl (Trade name)
Pharmakon1600-01503002
Sanasar
Sanasar (Trade name)
Saniscabis
Saniscabis (Trade name)
Scabagen
Scabanca
Scabicon
Scabicon (Trade name)
Scabide
Scabiex
Scabiex (Trade name)
Scabin
Scabin (Trade name)
Scabiozon
Scabisol
Scabisol (Trade name)
Scabitox
Scabitox (Trade name)
SCOBENOL
SMR000471875
Spasmodin
Spasmodine
SPECTRUM1503002
Spectrum5_001128
ST5406335
Tekoce
Tekoce (Trade name)
Vanzoate
Venzoate
Venzonate
WLN: RVO1R
Zilaben
安息香酸ベンジル [Japanese]





 
 
BENZYL BENZOATE

SYNONYMS: Benzyl Benzoate; benzyl benzoate; benzylbenzoate; benzyl benzoat; benzil benzoat; benzilbenzoat; banzil benzoat; banzilbenzoat; bensil bensoat; bensilbensoat; benzylbenzoat; bensil benzoat; bensilbenzoat; Benzylbenzoate; Benzyl Benzoat; Benzil Benzoat; Benzilbenzoat; Bensil Bensoat; Bensilbensoat; Benzylbenzoat; Bensil Benzoat; Bensilbenzoat; BENZYL BENZOATE; BENZYLBENZOATE; BENZYL BENZOAT; BENSİLBENZOAT; BENSİL BENZOAT; BENSİL BENSOAT; BENSİLBENSOAT; Acaril; Acarosan; Ansar; Antiscabiosum; Ascabiol; Benzanil; Benzemul; benzyl benzoate; Benzylbenzoaat Smeersel FNA; Novoscabin; BENZYL BENZOATE; 120-51-4; Ascabiol; Benylate; Novoscabin; Benzoic acid, phenylmethyl ester; Scabitox; Scobenol; Ascabin; Benzyl phenylformate; Benzoic acid, benzyl ester; Phenylmethyl benzoate; Benzoic acid benzyl ester; Benzylets; Colebenz; Peruscabin; Scabagen; Scabanca; Scabiozon; Vanzoate; Scabide; Benzyl benzenecarboxylate; benzylbenzoate; Antiscabiosum; Benzylis benzoas; Benzyl alcohol benzoic ester; Peruscabina; Spasmodin; Venzonate; Benzylum benzoicum; Benzylester kyseliny benzoove; Benzoesaeurebenzylester; Caswell No. 082; Benzylbenzenecarboxylate; Venzoate; FEMA Number 2138; Benzyl benzoate (natural); NSC 8081; UNII-N863NB338G; FEMA No. 2138HSDB 208; BENZOIC ACID PHENYLMETHYLESTER; EINECS 204-402-9; Benzylester kyseliny benzoove [Czech]; EPA Pesticide Chemical Code 009501; BRN 2049280; CHEMBL1239; AI3-00523; CHEBI:41237; SESFRYSPDFLNCH-UHFFFAOYSA-N; MFCD00003075; SBB058609; NCGC00094981-03; DSSTox_CID_9153; DSSTox_RID_78686; DSSTox_GSID_29153; Q-200696; Benzyl benzoate, analytical standard; Benzoate de benzyle; BZM; CAS-120-51-4; SMR000471875; benzylbenzoat; Benzyl benzoate [USP:JAN]; Acarobenzyl; Benzevan; Benzyl benzoate [USAN:JAN]; Benzyl benzoat; Benzoic acid phenylmethyl ester; Benzyl ester; 1dzm; Benylate (TN); benzoic acid benzyl; Benzoesaurebenzylester; Spectrum_001240; Spectrum2_000532; Spectrum3_001757; Spectrum4_000773; Spectrum5_001128; Benzyl benzoate 99+ %; ACMC-1C8AP; WLN: RVO1R; D0G1VX; Benzyl benzoate, >=99%; AC1L1DH0; SCHEMBL3038; BENZYL BENZOATE BP98; BSPBio_003494; KBioGR_001186; KBioSS_001720; 4-09-00-00307 (Beilstein Handbook Reference); KSC174Q0R; MLS001066412; MLS001336003; MLS001336004; DivK1c_000204; SPECTRUM1503002; SPBio_000543; Benzyl benzoate (JP17/USP); AC1Q661C; ZINC1021; DTXSID8029153; BENZOIC ACID,BENZYL ESTER; Benzyl benzoate, 99% 250g; CTK0H4808; HMS500K06, KBio1_000204; KBio2_001720; KBio2_004288; KBio2_006856; KBio3_002714; KS-00000UHX; NSC8081; MolPort-001-740-297; NINDS_000204; HMS1921P16; HMS2092F20; HMS2269D24; N863NB338G; Pharmakon1600-01503002; HY-B0935; NSC-8081; Tox21_111372; Tox21_201337; Tox21_303418; ANW-17509; BDBM50134035; CCG-39578; NSC758204; s4599; AKOS003495939; Benzyl benzoate, >=99%, FCC, FG; Tox21_111372_1; CHM0028580; DB00676; FCH2703790; LS-2573; MCULE-4369643785; NSC-758204; RL00855; RTR-003391; IDI1_000204; Benzyl benzoate, for synthesis, 99.0%; NCGC00094981-01; NCGC00094981-02; NCGC00094981-04; NCGC00094981-05; NCGC00094981-07i NCGC00257502-01; NCGC00258889-01; AC-17033; AN-22825; CC-24472; KB-75431; OR011551; ZB000222; SBI-0051748.P002; Benzoic acid-benzyl ester (Benzyl benzoate); DB-041563; TR-003391; B0064; FT-0622708 ST50406335; Benzyl benzoate, natural, >=99%, FCC, FG; Benzyl benzoate, ReagentPlus(R), >=99.0%; Benzyl benzoate, SAJ first grade, >=98.0%; Benzyl benzoate, tested according to Ph.Eur.; A19449; Benzyl benzoate, SAJ special grade, >=99.0%; C12537; D01138; AB00052298_07; Benzyl benzoate, Vetec(TM) reagent grade, 98%; Benzyl benzoate, meets USP testing specifications; C-24290; SR-01000763773; I14-6951; SR-01000763773-2; Benzoic acid-benzyl ester 5000 ng/microl in n-Hexane; Benzoic acid benzyl ester; Benzoic acid phenylmethyl ester; Benzyl benzoate, certified reference material, TraceCERT(R); Benzyl benzoate, United States Pharmacopeia (USP) Reference Standard; Benzyl benzoate, Pharmaceutical Secondary Standard; Certified Reference Material; InChI=1/C14H12O2/c15-14(13-9-5-2-6-10-13)16-11-12-7-3-1-4-8-12/h1-10H,11H; Benzyl Benzoate; Acaril; Acarosan; Ansar; Antiscabiosum; Ascabiol; Benzanil; Benzemul; benzyl benzoate; Benzylbenzoaat Smeersel FNA; Novoscabin; BENZYL BENZOATE; 120-51-4; Ascabiol; Benylate; Novoscabin; Benzoic acid, phenylmethyl ester; Scabitox; Scobenol; Ascabin; Benzyl phenylformate; Benzoic acid, benzyl ester; Phenylmethyl benzoate; Benzoic acid benzyl ester; Benzylets; Colebenz; Peruscabin; Scabagen; Scabanca; Scabiozon; Vanzoate; Scabide; Benzyl benzenecarboxylate; benzylbenzoate; Antiscabiosum; Benzylis benzoas; Benzyl alcohol benzoic ester; Peruscabina; Spasmodin; Venzonate; Benzylum benzoicum; Benzylester kyseliny benzoove; Benzoesaeurebenzylester; Caswell No. 082; Benzylbenzenecarboxylate; Venzoate; FEMA Number 2138; Benzyl benzoate (natural); NSC 8081; UNII-N863NB338G; FEMA No. 2138HSDB 208; BENZOIC ACID PHENYLMETHYLESTER; EINECS 204-402-9; Benzylester kyseliny benzoove [Czech]; EPA Pesticide Chemical Code 009501; BRN 2049280; CHEMBL1239; AI3-00523; CHEBI:41237; SESFRYSPDFLNCH-UHFFFAOYSA-N; MFCD00003075; SBB058609; NCGC00094981-03; DSSTox_CID_9153; DSSTox_RID_78686; DSSTox_GSID_29153; Q-200696; Benzyl benzoate, analytical standard; Benzoate de benzyle; BZM; CAS-120-51-4; SMR000471875; benzylbenzoat; Benzyl benzoate [USP:JAN]; Acarobenzyl; Benzevan; Benzyl benzoate [USAN:JAN]; Benzyl benzoat; Benzoic acid phenylmethyl ester; Benzyl ester; 1dzm; Benylate (TN); benzoic acid benzyl; Benzoesaurebenzylester; Spectrum_001240; Spectrum2_000532; Spectrum3_001757; Spectrum4_000773; Spectrum5_001128; Benzyl benzoate 99+ %; ACMC-1C8AP; WLN: RVO1R; D0G1VX; Benzyl benzoate, >=99%; AC1L1DH0; SCHEMBL3038; BENZYL BENZOATE BP98; BSPBio_003494; KBioGR_001186; KBioSS_001720; 4-09-00-00307 (Beilstein Handbook Reference); KSC174Q0R; MLS001066412; MLS001336003; MLS001336004; DivK1c_000204; SPECTRUM1503002; SPBio_000543; Benzyl benzoate (JP17/USP); AC1Q661C; ZINC1021; DTXSID8029153; BENZOIC ACID,BENZYL ESTER; Benzyl benzoate, 99% 250g; CTK0H4808; HMS500K06, KBio1_000204; KBio2_001720; KBio2_004288; KBio2_006856; KBio3_002714; KS-00000UHX; NSC8081; MolPort-001-740-297; NINDS_000204; HMS1921P16; HMS2092F20; HMS2269D24; N863NB338G; Pharmakon1600-01503002; HY-B0935; NSC-8081; Tox21_111372; Tox21_201337; Tox21_303418; ANW-17509; BDBM50134035; CCG-39578; NSC758204; s4599; AKOS003495939; Benzyl benzoate, >=99%, FCC, FG; Tox21_111372_1; CHM0028580; DB00676; FCH2703790; LS-2573; MCULE-4369643785; NSC-758204; RL00855; RTR-003391; IDI1_000204; Benzyl benzoate, for synthesis, 99.0%; NCGC00094981-01; NCGC00094981-02; NCGC00094981-04; NCGC00094981-05; NCGC00094981-07i NCGC00257502-01; NCGC00258889-01; AC-17033; AN-22825; CC-24472; KB-75431; OR011551; ZB000222; SBI-0051748.P002; Benzoic acid-benzyl ester (Benzyl benzoate); DB-041563; TR-003391; B0064; FT-0622708 ST50406335; Benzyl benzoate, natural, >=99%, FCC, FG; Benzyl benzoate, ReagentPlus(R), >=99.0%; Benzyl benzoate, SAJ first grade, >=98.0%; Benzyl benzoate, tested according to Ph.Eur.; A19449; Benzyl benzoate, SAJ special grade, >=99.0%; C12537; D01138; AB00052298_07; Benzyl benzoate, Vetec(TM) reagent grade, 98%; Benzyl benzoate, meets USP testing specifications; C-24290; SR-01000763773; I14-6951; SR-01000763773-2; Benzoic acid-benzyl ester 5000 ng/microl in n-Hexane; Benzoic acid benzyl ester; Benzoic acid phenylmethyl ester; Benzyl benzoate, certified reference material, TraceCERT(R); Benzyl benzoate, United States Pharmacopeia (USP) Reference Standard; Benzyl benzoate, Pharmaceutical Secondary Standard; Certified Reference Material; InChI=1/C14H12O2/c15-14(13-9-5-2-6-10-13)16-11-12-7-3-1-4-8-12/h1-10H,11H; 120-51-4 [RN]; 204-402-9 [EINECS]; Benzoate de benzyle [French] [ACD/IUPAC Name]; benzoic acid benzyl ester; benzoic acid, benzyl ester; Benzoic acid, phenylmethyl ester [ACD/Index Name]; Benzyl benzoate [ACD/IUPAC Name] [Wiki]; Benzylbenzoat [German]; Benzyl-benzoat [German] [ACD/IUPAC Name]; N863NB338G; phenylmethyl benzoate; [120-51-4]; 2049280 [Beilstein]; 347840-01-1 [RN]; 352431-26-6 [RN]; 4-09-00-00307; (Beilstein Handbook Reference) [Beilstein]; 613-62-7 [RN]; Acarilbial; Acarilbial (Trade name); Acaril-S; Acaril-S (Trade name); Acaril-S; Acarilbial; Acarsan; Acil; Antiscabiosum; Antiscabiosum für Kinder; Ascabiol; Ascalol; B.B. Lotion; BE BO; Benzalcor; Benzilbenzoat; Benzogal; Benzotal; Bezo; Finsarna; Gensarna; Miticocan; Novoscabin; Opele; Pharcobenzyl; Sanasar; Saniscabis; Scabicon; Scabiex; Scabin; Scabisol; Scabitox; Tekoce; Zilaben; Acarobenzyl; Acarobenzyl; Benylate; Benzevan; Benzoate de benzyle; Benzoes??urebenzylester; Benzoic acid phenylmethylester; Benzoic acid, benzyl ester; Benzoic acid, phenylmethyl ester; Benzyl benzoat; Benzylis benzoas; Phenylmethyl benzoate; Acarobenzyl; Benzevan; Benzoate de benzyle; Benzoesäurebenzylester; Benzyl benzoat; Benzylis benzoas; Phenylmethyl benzoate; Spasmodine; Acarsan; Acarsan (Trade name) Acil; Acil (Trade name); Antiscabiosum; Antiscabiosum (Trade name); Antiscabiosum für Kinder; Antiscabiosum für Kinder (Trade name); Ascabin; Ascabiol; Ascabiol (Trade name); Ascalol, Ascalol (Trade name); B.B. Lotion; B.B. Lotion (Trade name)BE BO; BE BO (Trade name); Benylate [Trade name]; Benylate (TN); Benzalcor; Benzalcor (Trade name); Benzevan; Benzilbenzoat; Benzilbenzoat (Trade name); Benzoate de benzyle [ACD/IUPAC Name]; Benzoesaeurebenzylester; Benzoesäurebenzylester; Benzogal; Benzogal (Trade name); benzoic acid phenylmethyl ester; BENZOIC ACID; PHENYLMETHYLESTER; BENZOIC ACID,BENZYL ESTER; Benzoic acid-benzyl ester (Benzyl benzoate); Benzoic acid-benzyl ester 100 ng/?l in Methanol; Benzoic acid-benzyl ester 100 ng/µl in Methanol; Benzoic acid-benzyl ester 5000 ng/?l in n-Hexane; Benzoic acid-benzyl ester 5000 ng/µl in n-Hexane; Benzotal; Benzotal (Trade name); Benzyl 2-naphthyl ether; Benzyl alcohol benzoic ester; Benzyl benzenecarboxylate; Benzyl benzoat; Benzyl benzoate (JP15/USP) [USP]; Benzyl benzoate (natural); Benzyl benzoate [USAN:JAN]; BENZYL BENZOATE BP98; Benzyl Benzoate-d12; Benzyl phenylformate; Benzylbenzenecarboxylate; benzylbenzoate; benzyl-benzoate; Benzyl-d5 Benzoate; Benzylester kyseliny benzoove; Benzylester kyseliny benzoove [Czech]; Benzylets; Benzylis benzoas; Benzylum benzoicum; Bezo; Bezo (Trade name); BSPBio_003494; BZM; CHEBI:41237; Colebenz; DG4200000; EINECS 204-402-9; Finsarna; Finsarna (Trade name); Gensarna; Gensarna (Trade name); IDI1_000204; InChI=1/C14H12O2/c15-14(13-9-5-2-6-10-13)16-11-12-7-3-1-4-8-12/h1-10H,11H; Mange Treatment; MFCD00003075 [MDL number]; Miticocan; Miticocan (Trade name); MLS001066412; NCGC00094981-01; NCGC00094981-02; NCGC00094981-03; Novoscabin; Novoscabin (Trade name); Opele; Opele (Trade name); Peruscabin; Peruscabina; Pharcobenzyl; Pharcobenzyl (Trade name); Pharmakon1600-01503002; Sanasar; Sanasar (Trade name); Saniscabis; Saniscabis (Trade name); Scabagen; Scabanca; Scabicon; Scabicon (Trade name); Scabide; Scabiex; Scabiex (Trade name); Scabin; Scabin (Trade name); Scabiozon; Scabisol; Scabisol (Trade name); Scabitox; Scabitox (Trade name); SCOBENOL; SMR000471875; Spasmodin; Spasmodine; SPECTRUM1503002; Spectrum5_001128; ST5406335; Tekoce; Tekoce (Trade name); UNII:N863NB338G; UNII-N863NB338G; Vanzoate; Venzoate; Venzonate; WLN: RVO1R; Zilaben; ???????? [Japanese]; BENZİL BENZOAT; BENZIL BENZOAT; BENZİL BENZOAT; BENZYL BENZOAT; BENZİL BENZOT; BENZİL BENZAT; BENZIL BENZIL; BEZIL BENZOAT; benzil benzoat; benzıl benzoat; benzıl benzoat; benzyl benzoat; benzyl ; benzoat; benzoate; benzyl benzoate; benzyl benzoat; benzil benzoat; benzıl benzoat; SESFRYSPDFLNCH-UHFFFAOYSA-N; Benzoic acid benzyl ester; antiscabiosum : ascabin : ascabiol : benylate : benzoic acid benzyl ester : benzoic acid phenyl methyl ester : benzyl alcohol benzoic ester : benzyl benzene carboxylate : benzyl phenyl formate : benzylets : colebenz : novoscabin : peruscabin : phenyl methyl benzoate : phenylmethyl benzoate : scabanca : vanzoate : venzonate : Aceto : Benzyl Benzoate : Advanced Biotech : benzyl benzoate 99pc min. natural; Benzyl 3-bromopropyl ether; Zylate;Scabide;ASCABIN;Benylate;Colebenz;Scabagen;Scabanca;Scabitox;Scobenol;Vanzoate; BENZYL BENZOATE; 120-51-4; Ascabiol; Benylate; Novoscabin; Benzoic acid benzyl ester; Benzoic acid, phenylmethyl ester; Ascabin; Scabitox; Scobenol; Benzyl phenylformate; Phenylmethyl benzoate; Benzoic acid, benzyl ester; Benzylets; Colebenz; Peruscabin; Scabagen; Scabanca; Scabiozon; Vanzoate; Scabide; Benzyl benzenecarboxylate; benzylbenzoate; Antiscabiosum; Benzylis benzoas; Benzyl alcohol benzoic ester; Peruscabina; Spasmodin; Venzonate; Benzylum benzoicum; Benzylester kyseliny benzoove; Benzoesaeurebenzylester; BENZOIC ACID PHENYLMETHYLESTER; Caswell No. 082; Benzylbenzenecarboxylate; Venzoate; FEMA Number 2138; Benzyl benzoate (natural); NSC 8081; UNII-N863NB338G; FEMA No. 2138; HSDB 208; EINECS 204-402-9; MFCD00003075; Benzylester kyseliny benzoove [Czech]; EPA Pesticide Chemical Code 009501; BRN 2049280; CHEMBL1239; AI3-00523; CHEBI:41237; SESFRYSPDFLNCH-UHFFFAOYSA-N; N863NB338G; NCGC00094981-03; Benzyl benzoate, 99+%; DSSTox_CID_9153; DSSTox_RID_78686; DSSTox_GSID_29153; Benzyl benzoate, analytical standard; Benzoate de benzyle; BZM; CAS-120-51-4; SMR000471875benzylbenzoat; Benzyl benzoate [USP:JAN]; Acarobenzyl; Benzevan; benzyl-benzoate; Benzyl benzoate [USAN:JAN]; Benzyl benzoat; Benzoic acid phenylmethyl ester; Benzyl ester; 1dzm; Benylate (TN); Benzoesaurebenzylester; Spectrum_001240; Benzoic acid-benzyl ester; Spectrum2_000532; Spectrum3_001757; Spectrum4_000773; Spectrum5_001128; Benzyl benzoate 99+ %; ACMC-1C8AP; WLN: RVO1R; Benzyl benzoate, >=99%; EC 204-402-9; AC1L1DH0; SCHEMBL3038; BENZYL BENZOATE BP98; BSPBio_003494; KBioGR_001186; KBioSS_001720; 4-09-00-00307 (Beilstein Handbook Reference); KSC174Q0R; MLS001066412; MLS001336003; MLS001336004; DivK1c_000204; SPECTRUM1503002; SPBio_000543; Benzyl benzoate (JP17/USP); AC1Q661C; ZINC1021; DTXSID8029153; BENZOIC ACID,BENZYL ESTER; CTK0H4808; HMS500K06; KBio1_000204; KBio2_001720; KBio2_004288; KBio2_006856; KBio3_002714; KS-00000UHX; NSC8081; NINDS_000204; HMS1921P16; HMS2092F20; HMS2269D24; Pharmakon1600-01503002; HY-B0935; NSC-8081; Tox21_111372; Tox21_201337; Tox21_303418; ANW-17509; BDBM50134035; CCG-39578; NSC758204; s4599; SBB058609; STL183088; AKOS003495939; Benzyl benzoate, >=99%, FCC, FG; Tox21_111372_1; DB00676; LS-2573; MCULE-4369643785; NSC-758204; RL00855; RTR-003391; IDI1_000204; Benzyl benzoate, for synthesis, 99.0%; NCGC00094981-01; NCGC00094981-02; NCGC00094981-04; NCGC00094981-05; NCGC00094981-07; NCGC00257502-01; NCGC00258889-01; AC-17033; AK308304; AN-22825; ZB000222; SBI-0051748.P002; DB-041563; TR-003391; B0064; FT-0622708; ST50406335; Benzyl benzoate, natural, >=99%, FCC, FG; Benzyl benzoate, ReagentPlus(R), >=99.0%; Benzyl benzoate, SAJ first grade, >=98.0%; Benzyl benzoate, tested according to Ph.Eur.; A14577; A19449; Benzyl benzoate, SAJ special grade, >=99.0%; C12537; D01138; AB00052298_07; Benzyl benzoate, Vetec(TM) reagent grade, 98%; Benzyl benzoate, meets USP testing specifications; SR-01000763773; Benzoic acid-benzyl ester 5000 microg/mL in Hexane; I14-6951; Q-200696; SR-01000763773-2; BRD-K52072429-001-06-1; Benzoic acid benzyl ester; Benzoic acid phenylmethyl ester; Benzyl benzoate, certified reference material, TraceCERT(R); Benzyl benzoate, United States Pharmacopeia (USP) Reference Standard; Benzyl benzoate,benzyl alcohol;phenylmethanol;benzenemethanol;100-51-6;phenylcarbinol;benzylic alcohol;Phenyl Methanol;Caswell No. 081F;.alpha.-Toluenol;Benzyl alcohol (natural);Alcool benzilico [DCIT];Itch-X;C6H5CH2OH;CHEMBL720;D05OIS;BENZYL ALCOHOL, ACS;EC 202-859-9;AC1L18SY;MolPort-001-783-216;HMS3264B16;Pharmakon1600-01502555;ZINC895302;Benzyl alcohol, analytical standard;Benzyl alcohol, AR, >=99.5%;HY-B0892;NSC-8044;Benzyl alcohol, anhydrous, 99.8%;Tox21_111172;Tox21_202447;Tox21_300044;BBL011938;LS-307;MFCD00004599;NSC760098;s4600;SBB058558;STL163453;Benzyl alcohol, >=99%, FCC, FG;AKOS000119907;AS04466;Benzyl alcohol, natural, >=98%, FG;BENZYL ALCOHOL, U.S.P./N.F.;CCG-213843;DB06770;LS41488;MCULE-6011707909;NSC-760098;RP18893;RTR-033774;NCGC00091865-02;NCGC00091865-03;NCGC00091865-04;NCGC00254154-01;NCGC00259996-01;1336-27-2;AJ-24171;BC222892;Benzyl alcohol, ACS reagent, >=99.0%;Benzyl alcohol, ReagentPlus(R), >=99%;Benzyl alcohol, USP, 98.0-100.5%;I765;SC-47293;ZB015017;KB-200532;TR-033774;B2378;Benzyl alcohol, tested according to Ph.Eur.;E1519;FT-0622812;ST24048908;ST51028320;Benzyl alcohol, p.a., ACS reagent, 99.0%;Benzyl alcohol, SAJ first grade, >=98.5%;3983-EP2269992A1;3983-EP2270004A1;3983-EP2270005A1;3983-EP2270011A1;3983-EP2270505A1;3983-EP2272516A2
Pharmaceutical Secondary Standard; Certified Reference Material Drugs and Supplement Benzyl Benzoate (Topical Route)Print Description and Brand Names Before Using Proper Use Precautions Side Effects Products and services The Mayo Clinic Diet: What is your weight-loss goal? 5-10 lbs, 11-25 lbs, or 25+ lbs Free E-newsletter Subscribe to Housecall Our general interest e-newsletter keeps you up to date on a wide variety of health topics. Sign up now Proper Use Benzyl benzoate usually comes with patient directions. Read them carefully before using this medicine. Use this medicine only as directed. Do not use more of it and do not use it more often than recommended on the label. To do so may increase the chance of absorption through the skin and the chance of side effects. Keep this medicine away from the eyes and other mucous membranes, such as the inside of the nose, because it may cause irritation . If you accidentally get some in your eyes, flush them thoroughly with water at once. Do not use benzyl benzoate on open wounds, such as cuts or sores on the skin or scalp. To do so may increase the amount of absorption, which may increase the chance of side effects. Your sexual partner or partners, especially, and all members of your household may need to be treated also, since the infestation may spread to persons in close contact. If these persons have not been examined for infestation or if you have any questions about this, check with your doctor. To use this medicine for lice: If your hair has any cream, lotion, ointment, or oil-based product on it, shampoo, rinse, and dry your hair and scalp well before applying benzyl benzoate. Apply enough medicine to thoroughly wet the dry hair and scalp or skin. Allow the medicine to remain on the affected areas for 24 hours. Then, thoroughly wash the affected areas with warm water and soap or regular shampoo. Rinse thoroughly and dry with a clean towel. After rinsing and drying, use a fine-toothed comb (less than 0.3 mm between the teeth) to remove any remaining nits (eggs) or nit shells from your hair, or, if you have fine hair, you may use a tweezer or your fingernails to pick nits out. To use this medicine for scabies: If your skin has any cream, lotion, ointment, or oil on it, wash, rinse, and dry your skin well before applying benzyl benzoate. If you take a bath or shower before using benzyl benzoate, dry the skin well before applying the medicine. Apply enough medicine to cover the entire skin surface from the neck down, including the soles of your feet, and rub in well. Allow the medicine to remain on the body for 24 hours. Then, thoroughly wash the body with warm water and soap. Rinse thoroughly and dry with a clean towel. Immediately after using benzyl benzoate, wash your hands to remove any medicine that may be on them. Treatment may need to be repeated for severe infestation. Dosing The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so. The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine. For topical dosage form (emulsion): For lice infestation: Adults-Use just one time. For severe cases, treatment may be repeated two or three times after twenty-four hours. Children- For infants: Use mixed with three parts of water, just one time. For older children: Use mixed with an equal quantity of water, just one time. For scabies infestation: Adults-Use just one time. For severe cases, treatment may be repeated after twenty-four hours one time anytime within five days. Children- For infants: Use mixed with three parts of water, just one time. For older children: Use mixed with an equal quantity of water, just one time. Storage Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing. Keep out of the reach of children. Do not keep outdated medicine or medicine no longer needed. Before Using Precautions Portions of this document last updated: Feb. 01, 2019 Copyright © 2019 IBM Watson Health. All rights reserved. Information is for End User's use only and may not be sold, redistributed or otherwise used for commercial purposes. Benzyl benzoate From Wikipedia, the free encyclopedia Jump to navigationJump to search benzoate Benzyl benzoate structure.svg Benzyl benzoate ball-and-stick.png Clinical data Trade names Ascabin, Ascabiol, Ascarbin, Tenutex, others Synonyms benzoic acid phenylmethyl ester, benzy alcohol benzoic ester ATC code P03AX01 (WHO) QP53AX11 (WHO) Identifiers CAS Number 120-51-4 PubChem CID 2345 DrugBank DB02775 ChemSpider 13856959 UNII KEGG D01138 ChEBI CHEBI:41237 ChEMBL ChEMBL1239 CompTox Dashboard (EPA) DTXSID8029153 Edit this at Wikidata ECHA InfoCard 100.004.003 Edit this at Wikidata Chemical and physical data Formula C14H12O2 Molar mass 212.248 g·mol-1 3D model (JSmol) Interactive image 1.118 g/cm3 g/cm3 Melting point 18 °C (64 °F) Boiling point 323 °C (613 °F) Solubility in water insoluble mg/mL (20 °C) SMILES InChI Benzyl benzoate (BnBzO), sold under the brand name Scabanca among others, is a medication and insect repellent.[1] As a medication it is used to treat scabies and lice.[2] For scabies either permethrin or malathion is typically preferred.[3] It is applied to the skin as a lotion.[2] Typically two to three applications are needed.[2] Side effects may include irritation of the skin.[2] It is not recommended in children.[3] It is also used in other animals; however, is toxic to cats.[1] How it works is unclear.[4] Benzyl benzoate was first studied medically in 1918.[1] It is on the World Health Organization's List of Essential Medicines, the most effective and safe medicines needed in a health system.[5] Benzyl benzoate is available as a generic medication.[3] The wholesale cost in the developing world is about US$0.21-0.53 per 100 mL.[6] It is not available for medical use in the United States.[1] In the United Kingdom it costs the NHS about £2.50 for 500 mL.[3]

 

Contents
1 Uses
1.1 Medical
1.2 Non-medical
2 Side effects
3 Chemistry
4 Production
5 References
Uses
Medical
Benzyl benzoate is an effective and inexpensive topical treatment for human scabies.[7] It has vasodilating and spasmolytic effects and is present in many asthma and whooping cough drugs.[8] It is also used as an excipient in some testosterone-replacement medications (like Nebido) for treating hypogonadism.[9] Benzyl benzoate is used as a topical acaricide, scabicide, and pediculicide in veterinary hospitals.[10] Non-medical Benzyl benzoate is used as a repellent for chiggers, ticks, and mosquitoes.[10] It is also used as a dye carrier, solvent for cellulose derivatives, plasticizer, and fixative in the perfume industry.[11] Side effects Benzyl benzoate has low acute toxicity in laboratory animals. It is rapidly hydrolyzed to benzoic acid and benzyl alcohol. Benzyl alcohol is subsequently metabolized to benzoic acid. The conjugates of benzoic acid (hippuric acid and the glucuronide of benzoic acid) are rapidly eliminated in urine.[1] When given in large doses to laboratory animals, benzyl benzoate can cause hyperexcitation, loss of coordination, ataxia, convulsions, and respiratory paralysis.[10] Benzyl benzoate can be a skin irritant when used as a topical scabicide.[7] Overdose can result in blistering and hives or a rash can occur as an allergic reaction.[12][13] As an excipient in some testosterone-replacement injectable medications, benzyl benzoate has been reported as a cause of anaphylaxis in a case in Australia.[14] Bayer includes this report in information for health professionals and recommends that physicians "should be aware of the potential for serious allergic reactions" to preparations of this type.[9] In Australia, reports to ADRAC, which evaluates reports of adverse drug reactions for the Therapeutic Goods Administration, show several reports of allergic issues since the anaphylaxis case from 2011.
Chemistry It is an organic compound with the formula C6H5CH2O2CC6H5. It is the ester of benzyl alcohol and benzoic acid. It forms either a viscous liquid or solid flakes and has a weak, sweet-balsamic odor. It occurs in a number of blossoms (e. g. tuberose, hyacinth) and is a component of Balsam of Peru and Tolu balsam.[11][15] 
Production Benzyl benzoate is produced industrially by the reaction of sodium benzoate with benzyl alcohol in the presence of a base, or by transesterification of methyl benzoate and benzyl alcohol.[8] It is a byproduct of benzoic acid synthesis by toluene oxidation.[11] It can also be synthesized by the Tishchenko reaction, using benzaldehyde with sodium benzylate (generated from sodium and benzyl alcohol) as catalyst:[16][17]

The Tishchenko reaction: benzaldehyde reacts to benzyl benzoate, the catalyst is generated in situ from sodium and benzyl alcohol
Benzyl benzoate# Organophosphate Malathion Other/ungrouped DimethiconeQuassiatoluidine (Crotamiton) #WHO-EM‡Withdrawn from marketClinical trials: †Phase III§Never to phas COMPOUND SUMMARY Benzyl benzoate PubChem CID: 2345 : Benzyl benzoate_small.png Benzyl benzoate_3D_Structure.png Find Similar Structures Chemical Safety: Irritant Environmental Hazard Laboratory Chemical Safety Summary (LCSS) Datasheet Molecular Formula: C14H12O2 Chemical Names: BENZYL BENZOATE 120-51-4 Ascabiol Benylate NovoscabinMore... Molecular Weight: 212.24 g/mol Dates: Modify: 2019-09-14 Create: 2005-03-25 Benzyl benzoate is a benzoate ester obtained by the formal condensation of benzoic acid with benzyl alcohol. It has been isolated from the plant species of the genus Polyalthia. It has a role as a scabicide, an acaricide and a plant metabolite. It is a benzyl ester and a benzoate ester. It derives from a benzoic acid.
Benzyl benzoate is one of the older preparations used to treat scabies. Scabies is a skin infection caused by the mite sarcoptes scabiei. It is characterised by severe itching (particularly at night), red spots, and may lead to a secondary infection. Benzyl benzoate is lethal to this mite and so is useful in the treatment of scabies. It is also used to treat lice infestation of the head and body. Benzyl benzoate is not the treatment of choice for scabies due to its irritant properties. from DrugBank Benzyl benzoate is one of the older preparations used to treat scabies. Scabies is a skin infection caused by the mite sarcoptes scabiei. It is characterised by severe itching (particularly at night), red spots, and may lead to a secondary infection. Benzyl benzoate is lethal to this mite and so is useful in the treatment of scabies. It is also used to treat lice infestation of the head and body. Benzyl benzoate is not the treatment of choice for scabies due to its irritant properties. from Human Metabolome Database (HMDB) 1Structures HelpNew Window 1.12D Structure HelpNew Window Find Similar Structures Get Image DownloadChemical Structure Depiction Benzyl benzoate.png COMPOUND SUMMARY Benzyl benzoate PubChem CID: 2345 Structure: Benzyl benzoate_small.png Benzyl benzoate_3D_Structure.png Find Similar Structures Chemical Safety: Irritant Environmental Hazard Laboratory Chemical Safety Summary (LCSS) Datasheet Molecular Formula: C14H12O2 Chemical Names: BENZYL BENZOATE 120-51-4 Ascabiol Benylate Novoscabin More... Molecular Weight: 212.24 g/mol Dates: Modify: 2019-09-14 Create: 2005-03-25

 

Benzyl benzoate is a benzoate ester obtained by the formal condensation of benzoic acid with benzyl alcohol. It has been isolated from the plant species of the genus Polyalthia. It has a role as a scabicide, an acaricide and a plant metabolite. It is a benzyl ester and a benzoate ester. It derives from a benzoic acid. from ChEBI Benzyl benzoate is one of the older preparations used to treat scabies. Scabies is a skin infection caused by the mite sarcoptes scabiei. It is characterised by severe itching (particularly at night), red spots, and may lead to a secondary infection. Benzyl benzoate is lethal to this mite and so is useful in the treatment of scabies. It is also used to treat lice infestation of the head and body. Benzyl benzoate is not the treatment of choice for scabies due to its irritant properties. from DrugBank Benzyl benzoate is one of the older preparations used to treat scabies. Scabies is a skin infection caused by the mite sarcoptes scabiei. It is characterised by severe itching (particularly at night), red spots, and may lead to a secondary infection. Benzyl benzoate is lethal to this mite and so is useful in the treatment of scabies. It is also used to treat lice infestation of the head and body. Benzyl benzoate is not the treatment of choice for scabies due to its irritant properties. from Human Metabolome Database (HMDB) 1Structures 

BENZOIC ACID PHENYLMETHYLESTER

Caswell No. 082 Benzylbenzenecarboxylate Venzoate FEMA Number 2138 Benzyl benzoate (natural) 8081 UNII-N863NB338G FEMA No. 2138 HSDB 208 EINECS 204-402-9 MFCD00003075 Benzylester kyseliny benzoove [Czech] EPA Pesticide Chemical Code 009501 BRN 2049280 CHEMBL1239 AI3-00523 CHEBI:41237 SESFRYSPDFLNCH-UHFFFAOYSA-N N863NB338G NCGC00094981-03 Benzyl benzoate, 99+% DSSTox_CID_9153 DSSTox_RID_78686 DSSTox_GSID_29153 Benzyl benzoate, analytical standard Benzoate de benzyle BZM CAS-120-51-4 SMR000471875 Benzyl benzoate [USP:JAN] Acarobenzyl Benzevan benzyl-benzoate Benzyl benzoate [USAN:JAN] Benzyl benzoat Benzoic acid phenylmethyl ester Benzyl ester 1dzm Benylate (TN) Benzoesaurebenzylester Spectrum_001240 Benzoic acid-benzyl ester Spectrum2_000532 Spectrum3_001757 Spectrum4_000773 Spectrum5_001128 Benzyl benzoate 99+ % ACMC-1C8AP WLN: RVO1R Benzyl benzoate, >=99% EC 204-402-9 AC1L1DH0 SCHEMBL3038 BENZYL BENZOATE BP98 BSPBio_003494 KBioGR_001186 KBioSS_001720 -09-00-00307 (Beilstein Handbook Reference) KSC174Q0R MLS001066412 MLS001336003 MLS001336004 DivK1c_000204 SPECTRUM1503002 SPBio_000543 Benzyl benzoate (JP17/USP) AC1Q661C ZINC1021 DTXSID8029153 BENZOIC ACID,BENZYL ESTER CTK0H4808 HMS500K06 KBio1_000204 KBio2_001720 KBio2_004288 KBio2_006856 KBio3_002714 KS-00000UHX NSC8081 NINDS_000204 HMS1921P16 HMS2092F20 HMS2269D24 Pharmakon1600-01503002 HY-B0935 NSC-8081 Tox21_111372 Tox21_201337 Tox21_303418 ANW-17509 CCG-39578 NSC758204 s4599 SBB058609 STL183088 AKOS003495939 Benzyl benzoate, >=99%, FCC, FG Tox21_111372_1 DB00676 LS-2573 MCULE-4369643785 NSC-758204 RL00855 RTR-003391 IDI1_000204 Benzyl benzoate, for synthesis, 99.0% NCGC00094981-01NCGC00094981-02 NCGC00094981-04 NCGC00094981-05 NCGC00094981-07 NCGC00257502-01 NCGC00258889-01 AC-17033 AK308304 AN-22825 ZB000222 SBI-0051748.P002 DB-041563 TR-003391 B0064 FT-0622708 ST50406335 Benzyl benzoate, natural, >=99%, FCC, FG benzoate, ReagentPlus(R), >=99.0% Benzyl benzoate, SAJ first grade, >=98.0% Benzyl benzoate, tested according to Ph.Eur. A14577 A19449 Benzyl benzoate, SAJ special grade, >=99.0% C12537 D01138 AB00052298_07 Benzyl benzoate, Vetec(TM) reagent grade, 98% Benzyl benzoate, meets USP testing specifications

 

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