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Bardac 2250

The Bardac® 2250 product shows a broad spectrum of activity against both gram-positive and gram-negative bacteria and is also effective on fungi and viruses, including those that are enveloped. Showing a high tolerance to hard water (above 350ppm), it remains active in the presence of heavy organic soiling. Its impressive surfactant and wetting properties make it one of the multipurpose biocides of choice for cooling systems and swimming pool water treatment as part of formulations.

This Bardac® 2250 product displays synergistic effects in combination with aldehydes and complexing agents, such as EDTA, but is incompatible with anionic detergents. It is registered in a large number of countries for numerous applications, including water treatment applications as well as hygiene and material protection applications.

Please check local regulations or consult your Lonza representative for further information.

Contains 50% solution of Dialkyl Dimethyl Ammonium Chloride (DDAC)
Shows a high tolerance to hard water (above 350ppm)
Available in drums, IBC’s and bulk


Bardac 2250 ürünü, hem gram pozitif hem de gram negatif bakterilere karşı geniş bir aktivite yelpazesi gösterir ve ayrıca zarflı olanlar da dahil olmak üzere mantar ve virüsler üzerinde etkilidir. Sert suya yüksek tolerans göstererek (350 ppm'nin üzerinde), ağır organik kirlilik varlığında aktif kalır. Etkileyici yüzey aktif maddesi ve ıslatma özellikleri, onu formülasyonların bir parçası olarak soğutma sistemleri ve yüzme havuzu suyu arıtımı için tercih edilen çok amaçlı biyositlerden biri yapar.

Bu Bardac 2250 ürünü, aldehitler ve EDTA gibi kompleks yapıcı maddelerle kombinasyon halinde sinerjik etkiler gösterir, ancak anyonik deterjanlarla uyumsuzdur. Su arıtma uygulamalarının yanı sıra hijyen ve malzeme koruma uygulamaları da dahil olmak üzere çok sayıda uygulama için çok sayıda ülkede kayıtlıdır.

Daha fazla bilgi için lütfen yerel düzenlemeleri kontrol edin veya ATAMAN KIMYA temsilcinize danışın.

% 50 Dialkyl Dimetil Amonyum Klorür (DDAC) çözeltisi içerir
Sert suya yüksek tolerans gösterir (350 ppm'nin üzerinde)
Varillerde, IBC’lerde ve toplu olarak mevcuttur
 
 

 
 
Didecyldimethylammonium chloride;BARDAC 2280,DDMAC,DDMAC 50,DDMAC 80;CAS No.7173-51-5. Chemical Name:Didecyl dimethyl ammonium chloride, quaternium 12,Bardac 2270,DDC 80, Didecyldimethyl ammonium chloride,DDAC,Bardac 22,didecyl(dimethyl)ammonium chloride,didecyl dimethylammonium chloride,Bardac 2280,
IUPAC Name: didecyl(dimethyl)azanium.IUPAC name: didecyl-dimethylammonium chloride. Other names: DDAC; Dimethyldidecylammonium chloride; 1-Decanaminium; N-decyl-N,N-dimethyl-, chloride; Didecyldimethylammonium chloride
;Didecyl dimethyl ammonium chloride; Quaternium-12


Didesildimetilamonyum klorür (DDAC), birçok biyosidal uygulamada kullanılan bir antiseptik / dezenfektandır. Moleküller arası etkileşimlerin bozulmasına ve lipit çift katmanlarının ayrılmasına neden olur. Geniş spektrumlu bir bakteri ve mantar öldürücüdür ve hastanelerde, otellerde ve endüstrilerde kullanılması tavsiye edilen çamaşırlar için dezenfektan temizleyici olarak kullanılabilir. Aynı zamanda jinekoloji, cerrahi, oftalmoloji, pediatri, OT'de ve cerrahi aletlerin, endoskopların ve yüzey dezenfeksiyonunun sterilizasyonu için kullanılır.
Tanım: Didecyldimethylammonium klorür, hastanelerde deterjan / dezenfektan olarak, yüzme havuzlarında yosun öldürücü olarak, mantar öldürücü olarak ve ahşapta termitlere karşı kullanılan kuaterner bir amonyum bileşiğidir. Bu bileşik, bir hastane çalışanında kontakt dermatite neden oldu, ayrıca glioksal ve bis- (aminopropil) - laurilamine duyarlıydı.
DDMAC, bir bakteriostat, deodorant, dezenfektan ve (veya) bir mikrobiyosit olarak kullanılan kuaterner amonyum bazlı antimikrobiyaldir.
Didecyldimethylammonium chloride (DDAC), bakterisidal, virüsidal ve fungisidal özellikleri nedeniyle çok sayıda üründe kullanılan bir dialkil-kuaterner amonyum bileşiğidir.

Kuaterner amonyum bileşikleri (QAC), düşük uçuculukları nedeniyle su bazlı yüzey dezenfektanları olarak yaygın olarak kullanılmaktadır ve geniş antimikrobiyal yeteneklerinden dolayı hastanelerde, otellerde ve tüketici ürünlerinde giderek daha fazla kullanılmaktadır (Zhang ve ark. 2015). Sağlık hizmetlerinde cerrahi aletlerin, endoskopların ve diğer tıbbi aletlerin dekontaminasyonu için klinik ortamlarda sıklıkla kullanılırlar. QAC'nin antiseptik, dezenfektan, deterjan ve koruyucu olarak kullanılması, mikrobiyal kontaminasyonu azaltmak ve patojen kaynaklı hastalık vakalarını azaltmak amacıyla ağızdan kullanılan (gargara) veya cilde veya gözlere uygulanan tüketici ürünlerine katılımını artırmıştır.

Tüm QAC, dört alkil yan zincir ile kalıcı olarak yüklü iyonlardır. Yapıları, pozitif yüklü bir nitrojen atomuna bağlı en az bir hidrofobik hidrokarbon zinciri ve çoğunlukla metil veya benzil grupları gibi çoğunlukla kısa zincirli ikameler olan diğer alkil gruplarını içerir. Biyosidal aktivite, alkil zinciri uzunluğu ile verilir (McBain ve diğerleri, 2004). Belirli mikrobiyal türleri hedeflemek için QAC yapısını uyarlama ve optimize etme yeteneği, son zamanlarda bu bileşiklerin tüketici ürünlerinde kullanım için kullanımını artırmıştır (Carson ve diğerleri, 2008). Dialkyl QAC, en yeni nesil QAC'yi temsil eder ve geniş bir aktivite yelpazesi sergiler. Bu yeni sentetik polimerik QAC, çözelti içinde anti-mikrobiyal, anti-statik ve yüzey aktif madde özellikleri sağlayan çok sayıda pozitif yüklü amin merkezleri içerir. Yaygın olarak kullanılan yeni QAC'lerden biri, didesildimetilamonyum klorürdür (DDAC). DDAC, Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa (Walsh ve ark. 2003), Legionella pneumophilia (Skaliy ve ark. 1980), Stachybotrys gibi çeşitli patojenlere karşı antimikrobiyal aktivite sergileyen geniş spektrumlu bir bakterisidal ve fungisidal biyosittir. zarfsız virüsler (Argy ve diğerleri 1999). Endüstriyel işlemler, yüzme havuzları ve su alanları, ahşap işleme, sağlık hizmetleri ve yiyecek işleme ve depolama dahil olmak üzere çeşitli uygulamalarda kullanılır (Ohnuma ve diğerleri 2011).

QAC 50 yılı aşkın süredir kullanılmaktadır ve genellikle güvenli olarak kabul edilmektedir; bununla birlikte, özellikle DDAC gibi daha yeni formülasyonlarla ilgili olarak bu bileşiklerin toksisitesini açıklayan çok sınırlı yayınlanmış araştırma bulunmaktadır. Ohnuma ve arkadaşları tarafından yapılan bir çalışma. (2011), C57BL / 6J farelerinde tek bir intratrakeal DDAC damlatmasını (60 ve 150 μg / kg) takiben pulmoner savunma sistemini inceledi. Bu yazarlar, bronkoalveolar (BAL) sıvısındaki laktat dehidrojenaz (LDH) aktivitesi ve protein konsantrasyonlarının artmasıyla kanıtlandığı üzere, yüksek doza maruz kalmanın, maruziyetten 1 gün sonra akciğer hasarına neden olduğunu bulmuşlardır. Ayrıca BAL'daki toplam hücrelerde (özellikle makrofajlar, nötrofiller ve lenfositler) ve maruziyetten 7 gün sonra interlökin (IL) -6 üretimindeki artışlar da vardı. Yazarlar ayrıca, DDAC maruziyetinin akciğerlerdeki oksidatif stresi ve antimikrobiyal belirteçleri (gen ekspresyonu ile değerlendirilen) değiştirdiğini ve lipopolisakkarid (LPS) ile sistemik birlikte maruz kalmanın, pulmoner inflamasyonda daha fazla artışa neden olduğunu ve bu da bakteriyel ajanlara duyarlılıkta potansiyel bir artışı düşündürdüğünü öne sürdüler.

Daha yeni bir çalışma, Sprague-Dawley sıçanlarında 2 haftalık soluma maruziyetini (Lim & Chung 2014) takiben DDAC'nin etkilerini araştırdı. En yüksek maruziyet konsantrasyonunda (3,6 mg / m3) vücut ağırlığındaki düşüşlerin yanı sıra, hematolojik ve kan biyokimyası parametrelerinde hiçbir değişiklik gözlenmemiş, BAL hücre sayımlarında ve hücre hasar parametrelerinde hafif değişiklikler gözlenmiştir. İlginç bir şekilde, yakın zamanda yapılan bir araştırma, DDAC'nin bir hayvan tesisinde kullanılmasının ardından laboratuvarın üreme performansının azaldığını gözlemledi.




Didecyldimethylammonium chloride (DDAC) is an antiseptic/disinfectant that is used in many biocidal applications. It causes disruption of intermolecular interactions and dissociation of lipid bilayers. It is a broad spectrum bactericidal and fungicidal and can be used as disinfectant cleaner for linen, recommended for use in hospitals, hotels and industries. It is also used in gynaecology, surgery, ophthalmology, pediatrics, OT, and for the sterilization of surgical instruments, endoscopes and surface disinfection.
Description: Didecyldimethylammonium chloride is a quaternary ammonium compound used as detergent/disinfectant in hospitals, as algicide in swimming pools, and as a fungicide and against termites in wood. This compound caused contact dermatitis in a hospital employee, also sensitive to glyoxal and bis-(aminopropyl)- laurylamine.
DDMAC is quaternary ammonium based antimicrobial used as a bacteriostat, deodorant, disinfectant and(or) a microbiocide.
Didecyldimethylammonium chloride (DDAC) is a dialkyl-quaternary ammonium compound that is used in numerous products for its bactericidal, virucidal and fungicidal properties

Quaternary ammonium compounds (QAC) are commonly used as water-based surface disinfectants due to their low volatility and they are increasingly being used in hospitals, hotels and in consumer products (Zhang et al. 2015) due to their broad antimicrobial capabilities. In healthcare settings they are frequently used in clinical settings for the decontamination of surgical instruments, endoscopes and other medical instruments. The use of QAC as antiseptics, disinfectants, detergents and preservatives has increased their incorporation into consumer products that are utilized orally (mouthwash) or applied to the skin or eyes for the purpose of decreasing microbial contamination and reducing the incidence of pathogen-induced illness.

All QAC are permanently charged ions with four alkyl side chains. Their structures contain at least one hydrophobic hydrocarbon chain linked to a positively charged nitrogen atom and other alkyl groups that are mostly short-chain substitutes such as methyl or benzyl groups. The biocidal activity is conferred through alkyl chain length (McBain et al. 2004). The ability to adapt and optimize QAC structure to target specific microbial species has recently increased the utilization of these compounds for use in consumer products (Carson et al. 2008). Dialkyl QAC represent the newest generation of QAC and exhibit a wide spectrum of activity. These new synthetic polymeric QAC contain multiple positively-charged amine centers that confer anti-microbial, anti-static, and surfactant properties in solution. One of the newer QAC in common use is didecyldimethylammonium chloride (DDAC). DDAC is a broad-spectrum bactericidal and fungicidal biocide that exhibits antimicrobial activity against several pathogens such as Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa (Walsh et al. 2003), Legionella pneumophilia (Skaliy et al. 1980), Stachybotrys chartarum and enveloped and non-enveloped viruses (Argy et al. 1999). It is used in several types of applications including: industrial processes, swimming pools and aquatic areas, wood treatment, healthcare and food handling and storage (Ohnuma et al. 2011).

QAC have been used for over 50 years and have generally been regarded as safe; however, there is very limited published research describing the toxicity of these compounds, especially regarding the newer formulations such as DDAC. A study conducted by Ohnuma et al. (2011) examined the pulmonary defense system following a single intratracheal instillation of DDAC (60 and 150 μg/kg) in C57BL/6J mice. Those authors found that exposure to the high dose induced lung injury as early as 1-d post-exposure, as evidenced by increased lactate dehydrogenase (LDH) activity and protein concentrations in the bronchoalveolar (BAL) fluid. There was also an increase in total cells in the BAL (specifically macrophages, neutrophils and lymphocytes), along with increases in interleukin (IL)-6 production by 7-days post-exposure. The authors also suggested that DDAC exposure altered oxidative stress and antimicrobial markers (evaluated by gene expression) in the lungs and systemic co-exposure with lipopolysaccharide (LPS) generated a further enhancement in pulmonary inflammation suggesting a potential increase in susceptibility to bacterial agents.

A more recent study investigated the effects of DDAC following a 2-week inhalation exposure (Lim & Chung 2014) in Sprague-Dawley rats. Aside from decreases in body weight at the highest exposure concentration (3.6 mg/m3), no changes in hematological and blood biochemistry parameters were observed and mild changes were observed in BAL cell counts and cell damage parameters. Interestingly, a recent study observed that, following the introduction of DDAC in an animal facility there was decreased reproductive performance of the laboratory mice. Additional examination identified decreases in fertility and fecundity including increased time to first litter, longer pregnancy intervals, fewer pups per litter and fewer pregnancies in mice following DDAC exposure (Melin et al. 2014).

Epidemiological data and case studies indicate that healthcare workers have an elevated risk for development of sensitization and allergic asthma from either dermal or inhalation exposure to chemicals compared to non-healthcare workers (Warshaw et al. 2008). Biocides such as QAC have been identified to be among the most common allergens in the healthcare profession (Bernstein et al. 1994; Purohit et al. 2000; Shaffer & Belsito 2000; Suneja & Belsito 2008; Gonzalez et al. 2014). A study evaluating 142 patients with suspected allergies to the most commonly used QAC, i.e. benzalkonium chloride (BAC) and benzethonium chloride (BEC), confirmed sensitization by patch test to these compounds in 20% of the patients and identified potential co-reactions between the two QAC in 85% of the subjects who tested positive (Dao et al. 2012).

While there have been fewer overall reported cases of sensitization to the newer formulations of QAC, allergic contact dermatitis and immediate-type allergic reactions caused by DDAC exposure have been recently reported. Four cases, which were confirmed by patch testing or open epicutaneous tests, describe contact dermatitis presenting in hospital and laboratory workers on the hands/wrists and face following exposure to DDAC present in a disinfectant (Dejobert et al. 1997; Dibo & Brasch 2001; Ruiz Oropeza et al. 2011). In addition, there is also a confirmed case of allergic contact dermatitis of the foot resulting from exposure to DDAC that was present in a shoe refresher spray (Mowitz & Ponten 2015). There has also been one case of immediate allergy reported in an individual in catering school who was exposed to DDAC in a cleaning product. This individual suffered from urticaria, facial angioedema and dyspnea within 10 min of exposure. A 20-min open epicutaneous test with the diluted cleaning product and DDAC confirmed immediate-type hypersensitivity (Houtappel et al. 2008). All symptoms in the individuals resolved when exposure to DDAC was eliminated.

While these studies suggest a role for QACs and DDAC in allergic disease, the exact mechanism of action for sensitization to these compounds remains to be investigated and explained. Due to the high potential for human exposure, epidemiological studies suggesting an association with allergic disease and the lack of dermal toxicological data, this study was performed to evaluate the irritancy and skin sensitization potential of DDAC using a murine model in an effort to assess its role in the development of allergic disease.




Дидецилдиметиламмоний хлорид (DDAC) - это антисептик / дезинфицирующее средство, которое используется во многих биоцидных приложениях. Это вызывает нарушение межмолекулярных взаимодействий и диссоциацию липидных бислоев. Это бактерицидное и фунгицидное средство широкого спектра действия, которое можно использовать в качестве дезинфицирующего средства для очистки белья, рекомендованного для использования в больницах, гостиницах и на производстве. Он также используется в гинекологии, хирургии, офтальмологии, педиатрии, ОТ, а также для стерилизации хирургических инструментов, эндоскопов и дезинфекции поверхностей.
Описание: Дидецилдиметиламмоний хлорид представляет собой соединение четвертичного аммония, используемое в качестве моющего / дезинфицирующего средства в больницах, в качестве альгицида в плавательных бассейнах, а также в качестве фунгицида и против термитов в древесине. Это соединение вызвало контактный дерматит у сотрудника больницы, также чувствительного к глиоксалю и бис- (аминопропил) - лауриламину.
DDMAC - это противомикробный препарат на основе четвертичного аммония, используемый в качестве бактериостата, дезодоранта, дезинфицирующего средства и (или) микробиоцида.
Дидецилдиметиламмонийхлорид (DDAC) представляет собой соединение диалкил-четвертичного аммония, которое используется во многих продуктах из-за его бактерицидных, вирулицидных и фунгицидных свойств.

Четвертичные аммониевые соединения (ЧАС) обычно используются в качестве дезинфицирующих средств на водной основе из-за их низкой летучести, и они все чаще используются в больницах, отелях и в потребительских товарах (Zhang et al. 2015) из-за их широких антимикробных свойств. В медицинских учреждениях они часто используются в клинических условиях для обеззараживания хирургических инструментов, эндоскопов и других медицинских инструментов. Использование ЧАС в качестве антисептиков, дезинфицирующих средств, детергентов и консервантов увеличило их включение в потребительские товары, которые используются орально (жидкость для полоскания рта) или наносятся на кожу или глаза с целью уменьшения микробного загрязнения и снижения частоты заболеваний, вызванных патогенами.

Все ЧАС - это постоянно заряженные ионы с четырьмя боковыми алкильными цепями. Их структуры содержат по крайней мере одну гидрофобную углеводородную цепь, связанную с положительно заряженным атомом азота, и другие алкильные группы, которые в основном являются короткоцепочечными заместителями, такими как метильная или бензильная группы. Биоцидная активность обеспечивается длиной алкильной цепи (McBain et al. 2004). Способность адаптировать и оптимизировать структуру ЧАС для нацеливания на определенные виды микробов недавно увеличила использование этих соединений для использования в потребительских товарах (Carson et al. 2008). Диалкил ЧАС представляют собой новейшее поколение ЧАС и проявляют широкий спектр активности. Эти новые синтетические полимерные ЧАС содержат несколько положительно заряженных аминных центров, которые придают раствору антимикробные, антистатические и поверхностно-активные свойства. Одним из наиболее новых широко используемых QAC является хлорид дидецилдиметиламмония (DDAC). DDAC представляет собой бактерицидный и фунгицидный биоцид широкого спектра действия, который проявляет антимикробную активность в отношении нескольких патогенов, таких как Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa (Walsh et al. 2003), Legionella pneumophilia (Skaliy et al. 1980), Stachybotrysite и Envelopar Chart и Envelopar Chart. вирусы без оболочки (Argy et al. 1999). Он используется в нескольких типах приложений, включая: промышленные процессы, бассейны и водные объекты, обработка древесины, здравоохранение, а также обработка и хранение пищевых продуктов (Ohnuma et al. 2011).

ЧАС используются более 50 лет и в целом считаются безопасными; однако существует очень ограниченное количество опубликованных исследований, описывающих токсичность этих соединений, особенно в отношении новых составов, таких как DDAC. Исследование, проведенное Ohnuma et al. (2011) исследовали систему защиты легких после однократной интратрахеальной инстилляции DDAC (60 и 150 мкг / кг) мышам C57BL / 6J. Эти авторы обнаружили, что воздействие высокой дозы индуцировало повреждение легких уже через 1 день после воздействия, о чем свидетельствует повышение активности лактатдегидрогеназы (ЛДГ) и концентрации белка в бронхоальвеолярной (БАЛ) жидкости. Также наблюдалось увеличение общего количества клеток в ЖБАЛ (в частности, макрофагов, нейтрофилов и лимфоцитов), наряду с увеличением выработки интерлейкина (ИЛ) -6 через 7 дней после воздействия. Авторы также предположили, что воздействие DDAC изменило окислительный стресс и антимикробные маркеры (оцениваемые по экспрессии генов) в легких, а системное совместное воздействие с липополисахаридом (ЛПС) вызвало дальнейшее усиление легочного воспаления, что указывает на потенциальное увеличение восприимчивости к бактериальным агентам.

В более позднем исследовании изучалось влияние DDAC после 2-недельного ингаляционного воздействия (Lim & Chung, 2014) на крыс Sprague-Dawley. Помимо снижения массы тела при максимальной концентрации воздействия (3,6 мг / м3), не наблюдалось никаких изменений гематологических и биохимических параметров крови, а также наблюдались незначительные изменения в количестве клеток ЖБАЛ и параметрах повреждения клеток. Интересно, что недавнее исследование показало, что после введения DDAC в животноводческий комплекс снизились репродуктивные показатели лаборатории.






Le chlorure de didécyldiméthylammonium (DDAC) est un antiseptique / désinfectant utilisé dans de nombreuses applications biocides. Il provoque une perturbation des interactions intermoléculaires et une dissociation des bicouches lipidiques. C'est un bactéricide et fongicide à large spectre et peut être utilisé comme nettoyant désinfectant pour le linge, recommandé pour une utilisation dans les hôpitaux, les hôtels et les industries. Il est également utilisé en gynécologie, chirurgie, ophtalmologie, pédiatrie, ergothérapie et pour la stérilisation des instruments chirurgicaux, des endoscopes et la désinfection des surfaces.
Description: Le chlorure de didécyldiméthylammonium est un composé d'ammonium quaternaire utilisé comme détergent / désinfectant dans les hôpitaux, comme algicide dans les piscines, comme fongicide et contre les termites dans le bois. Ce composé a provoqué une dermatite de contact chez un employé de l'hôpital, également sensible au glyoxal et à la bis- (aminopropyl) - laurylamine.
Le DDMAC est un antimicrobien à base d'ammonium quaternaire utilisé comme bactériostat, déodorant, désinfectant et (ou) microbiocide.
Le chlorure de didécyldiméthylammonium (DDAC) est un composé dialkyl-ammonium quaternaire utilisé dans de nombreux produits pour ses propriétés bactéricides, virucides et fongicides

Les composés d'ammonium quaternaire (QAC) sont couramment utilisés comme désinfectants de surface à base d'eau en raison de leur faible volatilité et ils sont de plus en plus utilisés dans les hôpitaux, les hôtels et dans les produits de consommation (Zhang et al.2015) en raison de leurs vastes capacités antimicrobiennes. Dans les établissements de soins de santé, ils sont fréquemment utilisés en milieu clinique pour la décontamination d'instruments chirurgicaux, d'endoscopes et d'autres instruments médicaux. L'utilisation du CAQ comme antiseptiques, désinfectants, détergents et conservateurs a augmenté leur incorporation dans les produits de consommation qui sont utilisés par voie orale (bain de bouche) ou appliqués sur la peau ou les yeux dans le but de réduire la contamination microbienne et de réduire l'incidence des maladies induites par des agents pathogènes.

Tous les QAC sont des ions chargés en permanence avec quatre chaînes latérales alkyle. Leurs structures contiennent au moins une chaîne hydrocarbonée hydrophobe liée à un atome d'azote chargé positivement et d'autres groupes alkyle qui sont pour la plupart des substituts à chaîne courte tels que des groupes méthyle ou benzyle. L'activité biocide est conférée par la longueur de la chaîne alkyle (McBain et al. 2004). La capacité d'adapter et d'optimiser la structure du CAQ pour cibler des espèces microbiennes spécifiques a récemment augmenté l'utilisation de ces composés dans les produits de consommation (Carson et al. 2008). Dialkyl QAC représente la dernière génération de QAC et présente un large spectre d'activité. Ces nouveaux QAC polymères synthétiques contiennent plusieurs centres aminés chargés positivement qui confèrent des propriétés antimicrobiennes, antistatiques et tensioactives en solution. Le chlorure de didécyldiméthylammonium (DDAC) est l'un des nouveaux QAC couramment utilisés. Le DDAC est un biocide bactéricide et fongicide à large spectre qui présente une activité antimicrobienne contre plusieurs agents pathogènes tels que Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa (Walsh et al.2003), Legionella pneumophilia (Skaliy et al.1980), Stachybot chartarum et enveloppé et virus non enveloppés (Argy et al. 1999). Il est utilisé dans plusieurs types d'applications, notamment: les processus industriels, les piscines et les espaces aquatiques, le traitement du bois, les soins de santé et la manipulation et le stockage des aliments (Ohnuma et al. 2011).

Les QAC sont utilisés depuis plus de 50 ans et sont généralement considérés comme sûrs; cependant, il existe des recherches publiées très limitées décrivant la toxicité de ces composés, en particulier en ce qui concerne les nouvelles formulations telles que le DDAC. Une étude menée par Ohnuma et al. (2011) ont examiné le système de défense pulmonaire après une seule instillation intratrachéale de DDAC (60 et 150 μg / kg) chez des souris C57BL / 6J. Ces auteurs ont constaté que l'exposition à la dose élevée induisait des lésions pulmonaires dès 1 jour après l'exposition, comme en témoignent l'augmentation de l'activité de la lactate déshydrogénase (LDH) et des concentrations de protéines dans le liquide bronchoalvéolaire (BAL). Il y avait également une augmentation du nombre total de cellules dans la BAL (en particulier les macrophages, les neutrophiles et les lymphocytes), ainsi qu'une augmentation de la production d'interleukine (IL) -6 7 jours après l'exposition. Les auteurs ont également suggéré que l'exposition au DDAC modifiait le stress oxydatif et les marqueurs antimicrobiens (évalués par l'expression génique) dans les poumons et que la coexposition systémique avec le lipopolysaccharide (LPS) avait généré une augmentation supplémentaire de l'inflammation pulmonaire suggérant une augmentation potentielle de la sensibilité aux agents bactériens.

Une étude plus récente a étudié les effets du DDAC après une exposition par inhalation de 2 semaines (Lim et Chung 2014) chez des rats Sprague-Dawley. Hormis une diminution du poids corporel à la concentration d'exposition la plus élevée (3,6 mg / m3), aucun changement des paramètres hématologiques et biochimiques sanguins n'a été observé et de légers changements ont été observés dans le nombre de cellules BAL et les paramètres de lésions cellulaires. Fait intéressant, une étude récente a observé que, suite à l'introduction du DDAC dans une animalerie, il y avait une diminution des performances de reproduction du laboratoire.


Synonyms: btc1010;bardac22;btco1010;Arquad 10;BARDAC2280;aliquat203;Hoe-S-2922;Aids006134;Aids-006134;Calgon H130

Chemical Properties: Liquid
Uses: Bardac 22 is a quaternary ammonium based antimicrobial used as a bacteriostat, deodorant, disinfectant and(or) a microbiocide.

Bardac 2250 and Bardac 2280 are twin chain dimethyl ammonium chlorides. When used as an active ingredient in FIFRA1 registered formulations such as hard surface disinfectants, sanitizers and/or certain types of water treatment formulations, these products have been found to provide superior biocidal action against a broad spectrum of microbial organisms such as: bacteria, fungi, viruses, and algae. This “third” generation quaternary ammonium compound delivers potent germicidal action in hard water and organic soil loads.

Bardac LF and LF-80 are composed of twin chain dimethyl ammonium chloride. The dioctyl dimethyl structure provides a controlled foam biocide, exhibiting low, fast breaking foam with exceptional dynamic controlled foam performance. When Bardac LF is used as an active ingredient in FIFRA1 registered formulations such as hard surface disinfectants, sanitizers and/or certain types of water treatment formulations, these products have been found to provide superior biocidal action against a broad spectrum of microbial organisms such as: bacteria, fungi, viruses, and algae. This “third” generation quaternary ammonium compound delivers potent germicidal action in hard water and organic soil loads.
DIDECYLDIMETHYLAMMONIUM CHLORIDE - Synonyme de 7173-51-5
Numéro CAS : 7173-51-5

Principaux synonymes
Noms français :
1-DECANAMINIUM, N-DECYL-N,N-DIMETHYL-, CHLORIDE
Chlorure de N,N-didécyl N,N-diméthyl ammonium
DIDECYL DIMETHYL AMMONIUM CHLORIDE
DIDECYLDIMETHYLAMMONIUM CHLORIDE

Noms anglais :
N,N-didecyl-N,N-dimethyl ammonium chloride


Didecyl dimethyl ammonium chloride;Didecyldimethylammonium chloride; Didecyldimethylammonium chloride(DDAC)

IUPAC Name: didecyl(dimethyl)azanium
Synonyms: N-Decyl-N,N-dimethyl-1-decanaminium Chloride, N-Decyl-N,N-dimethyl-1-decanaminium Chloride, Didecyldimethyl-ammonium Chloride, Didecyldimethylammonium Chloride, AQ 210, Acticide DDQ, Acticide DDQ 40, Arquad 10, Arquad 210, Arquad 210-50, Arquad 210-50E, Arquad 210-80, Arquad 210-80E, Arquad 210-85E, Asepas 3, Astop, BTC 1010, BTC 2250, BTC 99, Bardac 22, Bardac 2240, Bardac 2250, Bardac 2270E, Bardac 2280, Bio-Dac, Britewood Q, Britewood XL, Calgon H 130, Catiogen DDM, Catiogen DDM-PG, Cation DDC, Cation DDC 50, D 10P, DDAC, DDC 80, Dodigen 1881, H 130, H 130 (molluscicide), K-Sanit BP 80, Kamin RM 2D50A, KleenGrow, M 21080, Macrotrol MT 200, Maquat 4480E, Microbiocide B 74, Nissan Cation 2DB, Nissan Cation 2DB500E, Quartamin D 10E, Quartamin D 10P, Quaternium 12, Querton 210CL, Slaoff 91;Didecyldimethyl-ammonium Chloride
Product Information
Name: Didecyl Dimethyl Ammonium Chloride
Synonyms: N-Decyl-N,N-dimethyl-1-decanaminium Chloride; N-Decyl-N,N-dimethyl-1-decanaminium Chloride; Didecyldimethyl-ammonium Chloride; Didecyldimethylammonium Chloride; AQ 210; Acticide DDQ; Acticide DDQ 40;Arquad 10; Arquad 210; Arquad 210-50; Arquad 210-50E; Arquad 210-80; Arquad 210-80E; Arquad 210-85EAsepas 3Astop; BTC 1010; BTC 2250; BTC 99; Bardac 22; Bardac 2240;
Bardac 2250; Bardac 2270 E; Bardac 2280; Bio-Dac; Britewood Q; Britewood XL; Calgon H 130; Catiogen DDM; Catiogen DDM-PG; Cation DDC; Cation DDC 50D 10P; DDACDDC 80; Dodigen 1881; H 130H 130 (molluscicide)K-Sanit BP 80; Kamin RM 2D50A; KleenGrow M 21080; Macrotrol MT 200; Maquat 4480E; Microbiocide B 74; Nissan Cation 2DB; Nissan Cation 2DB500E; Quartamin D 10E; Quartamin D 10P; Quaternium 12; Querton 210CLSlaoff 91; N,N-Didecyl-N,N-dimethylammonium chloride; 1-Decanaminium,N-decyl-N,N-dimethyl-,chloride; Aliquat203; Bardac22; Bio-Dac50-22; Btc1010; Btco1010; Ddac; Didecyldimethyl-Ammoniuchloride; Didecyldimethylammoniumchloride; Dimethyldidecylammoniumchloride; N-Decyl-N,N-Dimethyl-1-Decanaminiuchloride; N-Decyl-N,N-dimethyl-1-decanaminium chloride; Didecyl-Dimethylammonium chloride;Didecyldimonium chloride; Didecildimethylammonium chloride; N-decyl-N,N-dimethyldecan-1-aminium chloride; N,N-Dimethyl-N,N-dioctadecylammonium chloride
CAS: 7173-51-5 
Description: Applications: Didecyl Dimethyl Ammonium Chloride is a compound that exhibits some fungacidal and antimirobial functions.
N-Decyl-N,N-dimethyl-1-decanaminium Chloride; N-Decyl-N,N-dimethyl-1-decanaminium Chloride; Didecyldimethyl-ammonium Chloride; Didecyldimethylammonium Chloride; AQ 210; Acticide DDQ; Acticide DDQ 40; Arquad 10; Arquad 210; Arquad 210-50; Arquad 210-50E; Arquad 210-80; Arquad 210-80E; Arquad 210-85E; Asepas 3; Astop; BTC 1010; BTC 2250; BTC 99; Bardac 22; Bardac 2240; Bardac 2250; Bardac 2270E; Bardac 2280; Bio-Dac; Britewood Q; Britewood XL; Calgon H 130; Catiogen DDM; Catiogen DDM-PG; Cation DDC; Cation DDC 50; D 10P; DDAC; DDC 80; Dodigen 1881; H 130; H 130 (molluscicide); K-Sanit BP 80; Kamin RM 2D50A; KleenGrow; M 21080; Macrotrol MT 200; Maquat 4480E; Microbiocide B 74; Nissan Cation 2DB; Nissan Cation 2DB500E; Quartamin D 10E; Quartamin D 10P; Quaternium 12; Querton 210CL; Slaoff 91; Sporekill; Stenquat 1010; Timbercote 2000; Tret-O-Lite XC 507

BUY Didecyl Dimethyl Ammonium Chloride
BUY Didecyldimethylammonium chloride
BUY DDMAC
1-Decanaminium, N-decyl-N,N-dimethyl-, chloride (1:1) [ACD/Index Name]
230-525-2 [EINECS]
3574954 [Beilstein]
7173-51-5 [RN]
BP6560000
Chlorure de N-décyl-N,N-diméthyl-1-décanaminium [French] [ACD/IUPAC Name]
DDAC
DIDECYLDIMETHYLAMMONIUM CHLORIDE
DIDECYLDIMONIUM CHLORIDE
Dimethyldidecylammonium chloride
MFCD00066262 [MDL number]
N-Decyl-N,N-dimethyl-1-decanaminium chloride [ACD/IUPAC Name]
N-Decyl-N,N-dimethyl-1-decanaminiumchlorid [German] [ACD/IUPAC Name]
N-Decyl-N,N-dimethyldecan-1-aminium chloride [ACD/IUPAC Name]
[7173-51-5]
126851-24-9 [RN]
154765-32-9 [RN]
18242-39-2 [RN]
1-Decanaminium, N-decyl-N,N-dimethyl-, chloride
1-Decanaminium,N-decyl-N,N-dimethyl-,chloride
20256-56-8 [RN]
Aliquat 203
ammonium compounds, quaternary, didecyldimethyl-, chloride
Ammonium, didecyldimethyl-, chloride
Arquad 10
Arquad 210-50
Asto
Astop
Bardac 22
Bardac 2250
Bardac 2270E
Bardac 2280
Bardac-22
Bio-Dac
Bio-dac 50-22
BIS(DECYL)DIMETHYLAZANIUM CHLORIDE
Britewood Q
Calgon H 130
Calgon H130
Chloride [ACD/IUPAC Name] [Wiki]
D 10P
Ddac(didecyldimethylammoniumchloride)
Didecyl dimethyl ammonium chloride, 80% aqueous solution
didecyl dimethylammonium chloride
didecyl(dimethyl)ammonium chloride
didecyl(dimethyl)azanium
didecyl(dimethyl)azanium and chloride
didecyl(dimethyl)azanium;chloride
Didecyldimethyl-ammoniuchloride
didecyl-dimethylammonium chloride
didecyl-dimethyl-ammonium chloride
didecyldimethylammoniumchloride
didecyl-dimethylazanium chloride
didecyl-dimethyl-azanium chloride
Dodigen 1881
EINECS 230-525-2
H 130 (molluscicide)
Maquat 4480E
N,N-didecyl-N,N-dimethylammonium chloride
N-Decyl-N,N-dimethyl 1-decanaminium chloride
N-Decyl-N,N-dimethyldecan-1-ammonium chloride
Nissan Cation 2DB
Odex Q
pBTC 1010
Quartamin D 10E
Quartamin D 10P
Quaternium 12
Quaternium-12
Querton 2100L
Querton 210CL
Slaoff 91
Timbercote 2000
Tret-O-Lite XC 507
塩化ジデシルジメチルアンモニウム [Japanese]


CAS Registry Number: 7173-51-5
CA Index Name: 1-Decanaminium, N-decyl-N,N-dimethyl-, chloride

Synonyms:
1-Decanaminium, N-decyl-N,N-dimethyl-, chloride
1-Decanaminium, N-decyl-N,N-dimethyl-, chloride (1:1)
AMMONIUM CHLORIDE, N,N-DIDECYL-N,N-DIMETHYL-
Ammonium, didecyldimethyl-, chloride
AQ 210
Arquad 10
Arquad 210
Arquad 210-50
Arquad 210-50E
Arquad 210-80
Arquad 210-80E
Astop
Bardac 22
Bardac 2250
Bardac 2270E
Bardac 2280
Bio-Dac
Britewood Q
Britewood XL
BTC 1010
BTC 2250
BTC 99
Calgon H 130
Catiogen DDM
Cation DDC
Chlorure de didecyldimethylammonium
cloruro de didecildimetilamonio
D 10P
DDAC
DDC 80
DIDECYL DIMETHYL AMMONIUM CHLORIDE
didecyldimethylammonium chloride
Didecyldimethylammoniumchlorid
DIDECYL-DIMETHYL-AMMONIUM-CHLORID
Didecyldimethylammounium chloride
Dimethyldidecylammonium chloride
Dodigen 1881
H 130
H 130 (molluscicide)
Kamin RM 2D50A
Macrotrol MT 200
Maquat 4480E
Microbiocide B 74
Nissan Cation 2DB
Quartamin D 10E
Quartamin D 10P
Quaternium 12
Querton 210CL
Slaoff 91
Sporekill
Stenquat 1010
Timbercote 2000
Tret-O-Lite XC 507

Chlorek didecylodimetyloamonium (pl)
Chlorek didecylodimetyloamonu (DDAC) (pl)
chlorure de didécyldiméthylammonium (fr)
Chlorure de didécyldiméthylammonium (DDAC) (fr)
cloreto de didecildimetilamónio (pt)
Cloreto de didecildimetilamónio (DDAC) (pt)
cloruro de didecildimetilamonio (es)
Cloruro de didecildimetilamonio (DDAC) (es)
cloruro di didecildimetilammonio (it)
Cloruro di didecildimetilammonio (DDAC) (it)
Clorură de didecildimetilamoniu (DDAC) (ro)
di(decyl)di(metyl)amónium-chlorid (sk)
Didecil-dimetil-ammónium-bromid (DDAC) (hu)
didecildimetilammónium-klorid (hu)
didecildimetilamonij-klorid (hr)
didecildimetilamonija hlorīds (lv)
Didecildimetilamonija hlorīds (DDAC) (lv)
Didecildimetilamonijev klorid (DDAC) (hr)
didecildimetilamonio chloridas (lt)
Didecildimetilamonio chloridas (DDAC) (lt)
didecildimetilamoniu clorura (ro)
didecilmetilamonijev klorid (sl)
didecyl(dimethyl)amonium-chlorid (cs)
didecyl(dimetyl)amónium-chlorid (DDAC) (sk)
Didecyldimethyl-ammoniumchloride (DDAC) (nl)
Didecyldimethylammonium chloride (DDAC) (mt)
didecyldimethylammoniumchlorid (da)
didecyldimethylammoniumchlorid (DDAC) (da)
didecyldimethylammoniumchloride (nl)
didecyldimethylamonium-chlorid (DDAC) (cs)
didecyldimetylammoniumklorid (no)
Didecyldimetylammoniumklorid (DDAC) (sv)
Didekyylidimetyyliammoniumkloridi (DDAC) (fi)
didekyylimetyyliammoniumkloridi (fi)
didetsüüldimetüülammooniumkloriid (et)
Didetsüüldimetüülammooniumkloriid (DDAC) (et)
χλωρίδιο του διδεκυλοδιμεθυλαμμωνίου (el)
Χλωριούχο διδεκυλοδιμεθυλαμμώνιο (DDAC) (el)
дидецилдиметиламониев хлорид (bg)
Дидецилдиметиламониев хлорид (DDAC) (bg)


1-Decanaminium, N-decyl-N,N-dimethyl-, chloride (1:1)
IUPAC names
1-Decanaminium, N-decyl-N,N-dimethyl-, chloride
Bardac 22
bis(decyl)dimethylazanium chloride
DDAC
didecyl(dimethyl)azanium chloride
didecyl(dimethyl)azanium;chloride
didecyl-dimethylammonium chloride
didecyl-dimethylazanium chloride
N,N,N-trimethylanilinium chloride
N,N-Didecyl-N,N-dimethylammonium chloride
N-decyl-N,N-dimethyldecan-1-aminium chloride
N-decyl-N,N-dimethyldecan-1-ammonium chloride

Trade names
Bardac

Other identifiers
126851-24-9
Other
CAS number
129186-13-6
Other
CAS number
154765-32-9
Other
CAS number
1632379-58-8
Other
CAS number
2923 90 00
PIC
Combined Nomenclature Code
446279-85-2
Other
CAS number
612-131-00-6

Index Number
7173-51-5


Didecyl dimethyl ammonium chloride
[CAS]

7173-51-5
[Synonyms]

DIDECYL-DIMETHYLAMMONIUM CHLORIDE
N-Decyl-N,N-dimethyl-1-decanaminium chloride
quaternium 12
1-Decanaminium,N-decyl-N,N-dimethyl-,chloride
aliquat203
bardac22
bio-dac50-22
btc1010
btco1010
ddac(didecyldimethylammoniumchloride)
didecyldimethyl-ammoniuchloride
didecyldimethylammoniumchloride(ddac)
dimethyldidecylammoniumchloride
n-decyl-n,n-dimethyl-1-decanaminiuchloride
DIDECYLDIMONIUM CHLORIDE
didecyl dimethyl Ammonium Chloride 50% solution in Toluene
didecyl dimethyl Ammonium Chloride 70% solution
Didecildimethylammonium chloride
BARDAC2280
Bardac(R) 22
[EINECS(EC#)]
230-525-2
7173-51-5
Didecyl dimethyl ammonium chloride
Didecyldimethylammonium chloride
N-decyl-N,N-dimethyldecan-1-aminium chloride
Astop
DDAC
Quaternium 12
Arquad 10
Bardac 22
Britewood Q
Dimethyldidecylammonium chloride
Bio-Dac
Quaternium-12
Odex Q
Quartamin D 10E
Quartamin D 10P
Nissan Cation 2DB
Timbercote 2000
Slaoff 91
Aliquat 203
Querton 210CL
1-Decanaminium, N-decyl-N,N-dimethyl-, chloride
Dodigen 1881
Bardac 2270E
Calgon H 130
Caswell No. 331A
Maquat 4480E
Bardac 2250
Bardac 2280
H 130 (molluscicide)
Arquad 210-50
Bio-dac 50-22
Tret-O-Lite XC 507
UNII-JXN40O9Y9B
DIDECYLDIMETHYLAMMONIUMCHLORIDE
DIDECYLDIMONIUM CHLORIDE
BTC 99
DDC 80
didecyl dimethylammonium chloride
BTCO 1010
D 10P
BTC 1010
N-Decyl-N,N-dimethyl-1-decanaminium chloride
Ammonium, didecyldimethyl-, chloride
EINECS 230-525-2
EPA Pesticide Chemical Code 069149
JXN40O9Y9B
didecyl(dimethyl)azanium;chloride
CHEBI:79935
1-Decanaminium, N-decyl-N,N-dimethyl-, chloride (1:1)
W-104509
Acticide
Sporekill
KleenGrow
Britewood XL
Acticide DDQ
Catiogen DDM
Cation DDC
Catiogen DDM-PG
Asepas 3
Septapav KhS 70
Acticide DDQ 40
Microbiocide B 74
Stenquat 1010
Arquad 210
Cation DDC 50
Cation DDC-80
Macrotrol MT 200
Microbiocide N 750
New Des 50
Bardac 2240
Kamin RM 2D50A
K-Sanit BP 80
Arquad 210-50E
Arquad 210-80E
Arquad 210-85E
Fentacare 1021-80
Arquad 210-80
Nissan Cation 2DB500E
Nissan Cation 2DB800E
Didecyldimethylammounium chloride
didecyl(dimethyl)azanium chloride
didecyl(dimethyl)ammonium chloride
BTC 2250
AQ 210
Bardac-22
Alfa Bergamon (TN)
Calgon H130
Querton 2100L
didecyl(dimethyl)ammonium
H 130
EC 230-525-2
N,N-DIDECYL-N,N-DIMETHYLAMMONIUM CHLORIDE
DIDECYLDIMETHYL AMMONIUM CHLORIDE
N-Decyl-N,N-dimethyl 1-decanaminium chloride
1-Decanaminium,N-decyl-N,N-dimethyl-,chloride
N-Decyl-N,N-dimethyldecan-1-ammonium chloride
Didecyldimethylammonium chloride, analytical standard
Didecyl dimethyl ammonium chloride, 80% aqueous solution
Didecyldimethylammonium chloride 

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