BENZOTRIAZOLE FINE GRANULA

BTA-FINE GRANULE;Benzotriazole, Benzotriazol, BTA, 1H-Benzotriazol, 1,2,3-Benzotriazol, BtaH, korozyon inhibitörü; fINE; FİNE; fine granular; Benzotriazole; Benzotriazol; BTA; 1H-Benzotriazol; 1,2,3-Benzotriazol; BtaH; 1,2,3-1H-Benzotriazole; 1,2,3-Benzotriazole; 1,2,3-triaza-1H; 1,2,3-triazaindene; 1H-1,2,3-Benzotriazole; 1H-benzo[1,2,3]triazole; 1H-Benzo[d][1,2,3]triazole; 1H-Benzotriazol; 1H-Benzotriazole; 1H-Benzotriazole; Benzotriazol; BTA; 1,2,3-Benztriazole; 1,2-aminoazophenylene; 1,2-Aminozophenylene; 2,3-diazaindole; 3aH Benzotriazole; azabenzimidazole; azaindazole; Azimidobenzene; aziminobenzene; benzene azimide; Benzisotriazole; benzo[1,2,3]triazole; benzo[d][1,2,3]triazole; Benzotriazole; Benzotriazole Needle Crystal; Benztriazole; Drometrizole; Irgastab I 489; ISK 3; Pseudoazimidobenzene; titaniumisopropyloxide; 1H-Benzotriazole; Benzotriazole; 1,2,3-BENZOTRIAZOLE; 2H-Benzotriazole; Azimidobenzene; 2H-Benzotriazole (IUPAC Name); 1,2,3-Benzotriazole; 1,2,3-triaza-1H-indene; 1,2,3-triazaindene; 1H-1,2,3-benzotriazole; 1H-benzotriazole; 2H-1,2,3-benzotriazole; benzotriazol; BTA; 1,2,-aminozophenylene; 1,2,3-triaza-1H-indene; 2,3-diazaindole; azimidobenzene; aziminobenzene; benzene azimide; benzisotriazole; Azimidobenzene, Cobratec 99; 1H-1,2,3-Benzotriazole; 2,3-Diazaindole; 1,2-Aminozophenylene; 1,2,3-Benztriazole; 1,2,3-Benzotriazole; 1,2,3-Triaza-1H-indene; 1,2,3-Triazaindene; Benzene Azimide; Benzene azimide; Benzisotriazole

 

 

Benzotriazole (BTA) fine granula is a heterocyclic compound containing three nitrogen atoms, with the chemical formula C6H5N3. This aromatic compound is colorless and polar and can be used in various fields. A synthesis of the BTA involves the reaction of o-phenylenediamine, sodium nitrite and acetic acid. The conversion proceeds via diazotization of one of the amine groups.The synthesis can be improved when the reaction is carried out at low temperatures (5-10 °C) and briefly irradiated in an ultrasonic bath.
Applications

Benzotriazole (BTA) fine granula has been known for its great versatility. Benzotriazole (BTA) fine granulahas already been used as a restrainer in photographic emulsions and as a reagent for the analytical determination of silver. More importantly, it has been extensively used as a corrosion inhibitor in the atmosphere and underwater. Also, its derivatives and their effectiveness as drug precursors have been drawing attention. Besides all the application mentioned above, the BTA can be used as antifreezes, heating and cooling systems, hydraulic fluids and vapor phase inhibitors as well.

Corrosion inhibitor

Benzotriazole (BTA) fine granula is an effective corrosion inhibitor for copper and its alloys by preventing undesirable surface reactions. It is known that a passive layer, consisting of a complex between copper and benzotriazole, is formed when copper is immersed in a solution containing benzotriazole. The passive layer is insoluble in aqueous and many organic solutions. There is a positive correlation between the thickness of the passive layer and the efficiency of preventing corrosion. BTA is used in conservation, notably for the treatment of bronze disease. The exact structure of the copper-BTA complex is controversial and many proposals have been suggested.

Drug precursor

Benzotriazole (BTA) fine granula derivatives have chemical and biological properties that are versatile in the pharmaceutical industry. Benzotriazole derivatives act as agonists for many proteins. For instance, vorozole and alizapride have useful inhibitory properties against different proteins and benzotriazole esters have been reported to work as mechanism-based inactivators for severe acute respiratory syndrome (SARS) 3CL protease. The methodology is not only limited to heterocyclization but was also successful for polynuclear hydrocarbons of small carbocyclic systems.
Benzotriazole (BTA) fine granula is also used in photographic developers and emulsion as a restrainer.

Environmental relevance

Benzotriazole (BTA) fine granula is fairly water-soluble, not readily degradable and has a limited sorption tendency. Hence, it is only partly removed in wastewater treatment plants and a substantial fraction reaches surface water such as rivers and lakes. Benzotriazole (BTA) fine granula is a bicyclic heterocyclic system consisting of three nitrogen atoms and fused benzene ring, shows wide range of biological and pharmacological activities. Benzotriazole can be synthesized using benzene-1,2-diamine and carboxylic acid. Benzotriazole posses wide spectrum of biological activities like including antibacterial, antifungal, antiviral, antiinflammatory, antihypertensive, analgesic properties. The present reviews attempted to gather the various developments in synthesis and biological activities of benzotriazole derivatives.