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DIETHYLAMINOETHANOL

Diethylethanolamine (DEAE) is a chemical compound with the molecular formula C6H15NO. 


Applications
Diethylethanolamine is used as a corrosion inhibitor in steam and condensate lines by neutralizing carbonic acid and scavenging oxygen.


It is used as a precursor in the production of a variety of chemical commodities such as the local anesthetic procaine. 
It can be reacted with 4-aminobenzoic acid to make procaine. DEAE can be used as a precursor for DEAE-cellulose resin, which is commonly used in ion exchange chromatography. 
DEAE can also be conveniently obtained from renewable sources. It is chemically stable and able to absorb carbon dioxide (CO2) from its surroundings.
In solution, it can decrease the surface tension of water when the temperature is increased.


Chemical synonyms:    2-Diethylaminoethanol; N,N-diethylethanolamine; 2-Diethylaminoethyl alcohol; Diethyl-(2-hydroxyethyl)amine, 2-; DEAE; DEEA; Diethylaminoethanol

Product description
Diethylaminoethanol (DEAE) is a clear liquid. It is used as a neutralizing amine for boiler water, coatings, etc.
Diethylaminoethanol (DEAE) is used as neutralizing agent and CO2 scavenger in boiler water. 
The ideal vapor pressure and vapor-liquid distribution properties of DEAE make it the best choice for pH adjustment of process water.

Other names: (Diethylamino)ethanol; DEAE; Ethanol, 2-(diethylamino)-; β-(Diethylamino)ethanol; Diethyl(2-hydroxyethyl)amine; N,N-Diethyl-N-(β-Hydroxyethyl)amine; N,N-Diethyl-2-hydroxyethylamine; N,N-Diethylethanolamine; N,N-Diethylmonoethanolamine; Pennad 150; 2-(Diethylamino)ethanol; 2-(Diethylamino)ethyl alcohol; 2-(N,N-Diethylamino)ethanol; 2-Hydroxytriethylamine; β-(Diethylamino)ethyl alcohol; (2-Hydroxyethyl)diethylamine; Diaethylaminoaethanol; Diethylethanolamine; N-(Diethylamino)ethanol; UN 2686; β-Hydroxytriethylamine; N,N-Diethylaminoethanol; Diethylmonoethanolamine; NSC 8759; A 22


Beyond its application in the water treatment segment, DEAE is also used as a neutralizing amine for indrustrial coatings and an intermediate for various surfactants.



colourless liquid

Colorless, hygroscopic liquid with a nauseating, ammonia-like odor. Experimentally determined detection and recognition odor threshold concentrations were 50 μg/m3 (11 ppbv) and 190 μg/m3 (40 ppbv), respectively (Hellman and Small, 1974).
Uses
Water-soluble salts; textile softeners; antirust formulations; fatty acid derivatives; pharmaceuticals; curing agent for resins; emulsifying agents in acid media; organic synthesis.
Uses
Anticorrosive agent; chemical intermediate for the production of emulsifiers, detergents, solubilizers, cosmetics, drugs, and textile finishing agents

ChEBI: A member of the class of ethanolamines that is aminoethanol in which the hydrogens of the amino group are replaced by ethyl groups.

2-Diethylaminoethanol (DEAE) is a tertiary amine produced by reaction of ethylene oxide or ethylene chlorhydrin and diethylamine (RTECS 1988). Itokazu (1987) has modified this process for manufacture of DEAE without eventual discoloration. Production in this country exceeds 2866 pounds per year (HSDB 1988).

A colorless liquid. Flash point 103-140°F. Less dense than water . Vapors heavier than air. Produces toxic oxides of nitrogen during combustion. Causes burns to the skin, eyes and mucous membranes.

Flammable. Soluble in water. Diethylaminoethanol is sensitive to moisture. Slowly hydrolyzes.

Diethylaminoethanol is an aminoalcohol. Amines are chemical bases. They neutralize acids to form salts plus water. These acid-base reactions are exothermic. The amount of heat that is evolved per mole of amine in a neutralization is largely independent of the strength of the amine as a base. Amines may be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen is generated by amines in combination with strong reducing agents, such as hydrides. Diethylaminoethanol can react with strong oxidizers and acids.




There is a lack of data regarding human toxicity of DEAE. There have been reported cases of skin and eye irritation, as well as dizziness and headache from workers in buildings which use DEAE as a steam additive (HSDB 1988). In this case, it is thought that contact through condensation and accumulation on surfaces is the cause of irritation as the sampling of air in these buildings yielded levels far below that recommended by NIOSH (1980) of a threshold limit value (TLV) time weighted average of 10 p.p.m. on the skin, or approximately 50 mg/m3 (ACGIH 1980). On the basis of data from Cornish (1965) and ACGIH (1980), the TLV is also below the level which will cause irritation directly to the eye. The greatest industrial hazard however, is thought to be to the eyes from contact with the fluid, which is comparable in severity to ammonium hydroxide as an eye irritant (ACGIH 1980).
DEAE is permitted by the U.S. Food and Drug Administration for some applications as a food additive. Applications include protective coatings for fresh fruits and vegetables, and as an additive in steam which directly contacts food products (excluding milk products). The National Research Council Committee on Toxicology (NRC 1983) has concluded that data on long-term, low-level airborne exposures of animals to DEAE for extrapolation to human health risks are severely lacking. This, combined with the lack of data concerning the concentrations of DEAE in humidified buildings did not allow sufficient information to set guidelines for long-term exposures or estimate the health risks from such exposures. The NRC was able to make some general recommendations based on the assumption that the nitrosation reactions (below) may occur, and that the amine should be considered as hazardous as the nitroso compound formed from it. The recommendations are:
1. The Navy should use boiler additives that are least likely to be nitrosated and that do not have other adverse effects on health that would preclude their use.
2. DEAE and morpholine should not be used in concert in a steam generating system when human exposure to the steam may occur.
3. When amines are used in steam generating systems, the air in rooms where the steam is used and the steam condensate is found should be monitored for the presence of amines and nitrosamines.
4. If DEAE, morpholine, or other nitrosatable volatile amines are used in steam generating systems where humans may be exposed to the steam, the amounts of amines added should be reduced as much as possible.
5. When amines are added to a steam generating system, they should be added continuously in small amounts, rather than in one large daily dose.

Industrial uses
DEAE is used in the pharmaceutical industry for the manufacture of the local anesthetics procaine and chloroquine; and in the chemical industry for the manufacture of water-soluble salts, fatty-acid derivatives, derivatives containing tertiary amine groups, emulsifiers, special soaps, cosmetics and textiles and fibers (HSDB 1988). It also is used in chromatography in chemistry and biochemistry laboratories (DEAE is useful as an ion-exchange matrix; DEAE-cellulose columns are used for purification of proteins and DNA, and DEAE-silica for phospholipid separations). In other industries DEAE is used in some antirust compositions and in textile softeners (Hawley 1977; HSDB 1988). It is also used widely as a steam additive in large buildings requiring humidifiers.

Carcinogenicity
DEAE was not mutagenic or clastogenic in a variety of in vitro and in vivo assays.

DEAE, when compared with other amino alcohols, was observed to be biologically undecomposable in an experiment using activated sludge
Metabolism
The absorption of DEAE (administered orally as DEAE acid malate or 'Cerebrol') in healthy adult rats is very rapid, reaching a peak plasma level in 30 min (Bismut et al 1986). The biological half-life is 3.5 h with 39% of the excreted product appearing in the urine after 48 h (Bismut et al 1986). In an earlier study, Schulte et al (1972) demonstrated that in rats, following a single oral dose, excretion occurs mainly through the kidneys with 37-59% being eliminated in the first 24 h. After 48 h, elimination was independent of dose. The brain and spinal cord showed the highest concentration after 7 d. Metabolites produced were observed to be diethylaminoethanol N-oxide, diethylaminoacetic acid, and ethylaminoethanol.


Preparation
Diethylethanolamine is prepared commercially by the reaction of diethylamine and ethylene oxide.

2-diethylaminoethanol is a member of the class of ethanolamines that is aminoethanol in which the hydrogens of the amino group are replaced by ethyl groups. 
It is a member of ethanolamines, a tertiary amino compound and a primary alcohol. It derives from an ethanolamine. It derives from a hydride of a triethylamine.

2-diethylaminoethanol appears as a colorless liquid. Flash point 103-140°F. Less dense than water . Vapors heavier than air. Produces toxic oxides of nitrogen during combustion. 
Causes burns to the skin, eyes and mucous membranes.
DEEA;DEAE;100-37-8;Dehydasal;Rotec A.O.;Pennad 150;Perdilaton;-Diethylamino;Loramine AMB 13;Dietyleneglycol

Diethylaminoethanol


Chemical Synonym
2-Diethylaminoethanol; N,N-diethylethanolamine; 2-Diethylaminoethyl alcohol; Diethyl-(2-hydroxyethyl)amine, 2-; DEAE

Product Description
Diethylaminoethanol (DEAE) is a clear liquid. It is used as a neutralizing amine for boiler water, coatings, etc.
Diethylaminoethanol (DEAE) is used as neutralizing agent and CO2 scavenger in boiler water. The ideal vapor pressure and vapor-liquid distribution properties of DEAE make it the best choice for pH adjustment of process water.

Beyond its application in the water treatment segment, DEAE is also used as a neutralizing amine for indrustrial coatings and an intermediate for various surfactants.

Diethylethanolamine (DEAE) is a chemical compound with the molecular formula C6H15NO. It is used as a precursor in the production of a variety of chemical commodities such as the local anesthetic procaine. It can be reacted with 4-aminobenzoic acid to make procaine. DEAE can be used as a precursor for DEAE-cellulose resin, which is commonly used in ion exchange chromatography. DEAE can also be conveniently obtained from renewable sources. It is chemically stable and able to absorb carbon dioxide (CO2) from its surroundings. In solution, it can decrease the surface tension of water when the temperature is increased.


2-diethylaminoethanol (CHEBI:52153) has functional parent ethanolamine 
2-diethylaminoethanol (CHEBI:52153) has parent hydride triethylamine 
2-diethylaminoethanol (CHEBI:52153) is a ethanolamines 
2-diethylaminoethanol (CHEBI:52153) is a primary alcohol 
2-diethylaminoethanol (CHEBI:52153) is a tertiary amino compound 



Typical Properties

Property Typical Value, Units
General
Molecular Formula: C6H15NO
Molecular Weightç117.2 g/mol
Autoignition Temperature: 320 °C
Boiling Point: 162.36 °C
Coefficient of cubical expansion: 0.00109/ °C
Density@ 20°C: 0.88 g/cm3
Dissociation constant, pKa@ 25°C: 10.1
Flash PoinT Tag Closed Cup: 51.7 °C
Freezing Point: -68 °C
Octanol-water partition coefficient, log Pow@ 23°C: 0.21
pH 100 g/l @ 20°C: 11.5
Vapor Density(air = 1): 4
Vapor Pressure@ 22.4°C: 2 hPa
Viscosity@ 25°C: 4.002 mPa·s
Water solubility: Soluble


(C2H5)2NH + cyclo(CH2CH2)O → (C2H5)2NCH2CH2OH
It is also possible to prepare it by the reaction of diethylamine and ethylene chlorohydrin.

Safety
Diethylethanolamine is an irritant to the eyes, skin, and respiratory system. 

Preferred IUPAC name
2-(Diethylamino)ethan-1-ol
Other names
2-(Diethylamino)ethanol
Diethylaminoethanol
2-Diethylaminoethanol
N,N-Diethyl-2-aminoethanol
N,N-Diethylethanolamine
Diethyl(2-hydroxyethyl)amine
(2-Hydroxyethyl)diethylamine
2-Diethylaminoethyl alcohol
2-Hydroxytriethylamine
Identifiers
CAS Number
100-37-8 check



Chemical formula: C6H15NO
Molar mass: 117.192 g·mol−1
Appearance: Colourless liquid
Odor: Ammoniacal
Density: 884 mg mL−1
Melting point: −70 °C;
Boiling point:161.1 °C
Solubility in water: miscible
log P: 0.769
Vapor pressure: 100 Pa (at 20 °C)
Refractive index (nD): 1.441–1.442




2-diethyl aminoethanol
2-diethylamino-ethanol
2-(diethylamino)ethan-1-ol
.beta.-(diethylamino)ethanol
(diethylamino)ethanol
2-(diethylamino)ethanol
2-(N,N-diethylamino)ethanol
2-N-(diethylamino)ethanol
.beta.-(diethylamino)ethyl alcohol
2-(diethylamino)ethyl alcohol
diethylaminoethanol
2-diethylaminoethanol
2-N-diethylaminoethanol
2-diethylaminoethanol [UN2686] [Corrosive]
diethylethanolamine
diethylmonoethanolamine
2-hydroxytriethylamine
2-(diethylamino)ethanol
2-(dimethylamino)ethanol hydrochloride
2-(N,N-dimethylamino)ethanol hydrochloride
2-diethylaminoethanol
2-diethylaminoethanol hydrochloride
2-diethylaminoethanol hydrochloride, 14C-labeled
2-diethylaminoethanol sulfate (2:1)
2-diethylaminoethanol tartrate
2-diethylaminoethanol, sodium salt

DEAE
deanol hydrochloride
diethylaminoethanol
diethylethanolamine
ethanol, 2-(dimethylamino)-, hydrochloride (1:1)
ethanol, 2-dimethylamino-, hydrochloride
N,N-diethylethanolamine
2-(Diethylamino)ethanol
2-Diethylaminoethanol
N,N-Diethylethanolamine
100-37-8
DIETHYLAMINOETHANOL
Diethylethanolamine
DEAE
Ethanol, 2-(diethylamino)-
(Diethylamino)ethanol
N,N-Diethyl-2-aminoethanol
(2-Hydroxyethyl)diethylamine
Diethyl(2-hydroxyethyl)amine
Diethylmonoethanolamine
2-Hydroxytriethylamine
Pennad 150
Diaethylaminoaethanol
2-(Diethylamino)Ethan-1-Ol
2-(N,N-Diethylamino)ethanol
N,N-Diethylmonoethanolamine
N,N-Diethyl-2-hydroxyethylamine
beta-Diethylaminoethanol
beta-Hydroxytriethylamine
2-(Diethylamino)ethyl alcohol
N-Diethylaminoethanol
2-diethylamino-ethanol
2-N-Diethylaminoethanol
diethyl ethanolamine
Diethylamino ethanol
DEEA
beta-Diethylaminoethyl alcohol
N-(Diethylamino)ethanol
N,N-Diethyl-N-(beta-hydroxyethyl)amine
NSC 8759
UNII-S6DL4M053U
C6H15NO
Diaethylaminoaethanol [German]
CCRIS 4793
HSDB 329
N,N-Diethylaminoethanol
n,n-diethyl ethanolamine
2-(diethylamino)-ethanol
EINECS 202-845-2
UN2686
2-N-(Diethylamino)ethanol
.beta.-(Diethylamino)ethanol
ETHANOL,2-DIETHYLAMINO
AI3-16309
S6DL4M053U
beta-(Diethylamino)ethyl alcohol
CHEBI:52153
.beta.-(Diethylamino)ethyl alcohol
N,N-Diethyl-N-(.beta.-hydroxyethyl)amine
2-Diethylaminoethanol [UN2686] [Corrosive]
N,N-Diethylethanolamine, 99%
CAS-100-37-8
Dehydasal
2-Diethylamino
Diathylaminoathanol
2-Hydroxy
MFCD00002850
n,n-diethyl-aminoethanol
N, N-Diethylethanolamine
beta-(Diethylamino)ethanol
N,N-diethyl ethanol amine
.beta.-Hydroxytriethylamine
EC 202-845-2
SCHEMBL3114
2-Diethylaminoethanol, 9CI
CHEMBL1183

2-(Diethylamino)ethanol [ACD/IUPAC Name]
100-37-8 [RN]
2-(Diethylamino)ethanol [German] [ACD/IUPAC Name]
2-(Diéthylamino)éthanol [French] [ACD/IUPAC Name]
202-845-2 [EINECS]
2-Diethylaminoethanol
2-Hydroxytriethylamine
741863 [Beilstein]
DEAE
DEEA
Diethylaminoethanol
Ethanol, 2-(diethylamino)- [ACD/Index Name]
KK5075000
N,N-DIETHYLETHANOLAMINE
S6DL4M053U
(2-HYDROXYETHYL)DIETHYLAMINE
(DIETHYLAMINO)ETHANOL
1-(Diethylamino)ethanol [ACD/IUPAC Name]
2-(Diethylamino)-ethanol
2-(Diethylamino)ethyl alcohol
2-(Diethylamino)ethyl cellulose
2-(DIETHYLAMONO)ETHANOL
2-(N,N-Diethylamino)ethanol
2-Diethylamino
2-diethylamino-ethanol
2-Diethylaminoethanol, 9CI
2-N-(Diethylamino)ethanol
2-N-Diethylaminoethanol
32954-58-8 [RN]
64346-24-3 [RN]
9013-34-7 [RN]
DEAE|2-(DIETHYLAMINO)ETHAN-1-OL
Dehydasal
Di??thylamino??thanol
Diaethylaminoaethanol
Diaethylaminoaethanol [German]
Diaethylaminoaethanol(german)
Diethyl ethanolamine
Diethyl ethanolamine;Diethylaminoethanol;2-Hydroxytriethylamine
Diethyl(2-hydroxyethyl)amine
Diethylamino ethanol
Diethylamlnoethanol
DIETHYLETHANOLAMINE
Diethylmonoethanolamine
ETHANOL,2-DIETHYLAMINO
ipomeanol
N-(2-Hydroxyethyl)diethylamine
N-(Diethylamino)ethanol
N, N-Diethylethanolamine
N,​N-​Diethylethanolamine(2-Diethylaminoethanol)
N,N-DIETHYL ETHANOLAMINE
N,N-Diethyl-2-aminoethanol
N,N-Diethyl-2-hydroxyethylamine
N,N-Diethylaminoethanol
N,N-Diethylmonoethanolamine
N,N-Diethyl-N-(β-hydroxyethyl)amine
N,N-Diethyl-N-(β-hydroxyethyl)amine
N-Diethylaminoethanol
Pennad 150
Perdilaton
Q2N2 & 2 [WLN]
UN 2686
UNII:S6DL4M053U
UNII-S6DL4M053U
VS-03234
β-(Diethylamino)ethanol
β-(Diethylamino)ethanol
β-(diethylamino)ethyl alcohol
β-(Diethylamino)ethyl alcohol
β-Diethylaminoethanol
β-Diethylaminoethyl alcohol
β-hydroxytriethylamine
β-Hydroxytriethylamine


chloroprocaine (CHEBI:3636) has functional parent 2-diethylaminoethanol 
dicyclomine (CHEBI:4514) has functional parent 2-diethylaminoethanol 
oxybuprocaine (CHEBI:309594) has functional parent 2-diethylaminoethanol 
procaine (CHEBI:8430) has functional parent 2-diethylaminoethanol 



2-diethylaminoethanol
2-DIETHYLAMINOETHANOL
2-diethylaminoethanol
2-diethylaminoethanol; N,N-diethylethanolamine

Diethylaminoethanol
N,N-diethylethanolamine
Translated names
2-(diethylamino)ethan-1-ol (cs)
2-(dietylamino)etanol (sk)
2-(dietyloamino)etanol (pl)
2-diethylaminoethanol (da)
2-Diethylaminoethanol (de)
2-diethylaminoethanol (nl)
2-dietil-aminoetanol (hr)
2-dietilaminoetanol (es)
2-dietilaminoetanol (hu)
2-dietilaminoetanol (pt)
2-dietilaminoetanol (ro)
2-dietilaminoetanol (sl)
2-dietilaminoetanolis (lt)
2-dietilaminoetanolo (it)
2-dietilaminoetanols (lv)
2-dietylaminoetanol (no)
2-dietylaminoetanol (sv)
2-dietyyliaminoetanoli (fi)
2-dietüülaminoetanool (et)
2-diéthylaminoéthanol; N,N-diéthyléthanolamine (fr)
2-διαιθυλαμινοαιθανόλ (el)
2-диетиламиноетанол (bg)
<I>N,N</I>-dietil-etanolamin (hr)
N,N-diethylethanolamin (cs)
N,N-dietiletanolamin (hu)
N,N-dietiletanolamin (sl)
N,N-dietiletanolamina (ro)
N,N-dietiletanolaminas (lt)
N,N-dietiletanolamīns (lv)
N,N-dietyletanolamín (sk)
N,N-dietyloetanoloamina (pl)
N,N-dietüületanoolamiin (et)
N,N-Dimethylethanolamin (de)
N,N-диетилетаноламин (bg)

CAS names
Ethanol, 2-(diethylamino)-

IUPAC names
2-(diethylamino)ethan-1-ol
2-(diethylamino)ethanol
2-(diethylamino)ethanol
2-DIETHYLAMINOETHANOL
2-Diethylaminoethanol
2-diethylaminoethanol
2-Diethylaminoethanol 
DEAE
Diethylaminoethanol
Diethylaminoethanol
Ethanol, 2-(diethylamino)-
N, N-diethylethanolamin
N,N-Diethylethanolamine
N,N-diethylethanolamine

Trade names
(2-Hydroxyethyl)diethylamine
(2-Hydroxyethyl)diethylamine (Diethylamino)ethanol .beta.-(Diethylamino)ethanol 2-(Diethylamino)ethanol 2-(Diethylamino)ethyl alcohol 2-(N,N-Diethylamino)ethanol 2-Diethylaminoethanol 2-Hydroxytriethylamine DEAE Diethyl(2-hydroxyethyl)amine Diethylethanolamin Diethylethanolamine Diethylmonoethanolamine Ethanol, 2-(diethylamino)- (8CI, 9CI) MKS N,N-Diethyl-2-aminoethanol N,N-Diethyl-2-hydroxyethylamine N,N-Diethyl-N-(.beta.-hydroxyethyl)amine N,N-Diethylethanolamine N,N-Diethylmonoethanolamine N-(2-Hydroxyethyl)diethylamine Pennad 150
(Diethylamino)ethanol
.beta.-(Diethylamino)ethanol
2-(Diethylamino)ethanol
2-(Diethylamino)ethyl alcohol
2-(N,N-Diethylamino)ethanol
2-Diethylaminoethanol
2-Hydroxytriethylamine
DEAE
Diethyl(2-hydroxyethyl)amine
Diethylethanolamin
Diethylethanolamine
Diethylmonoethanolamine
Ethanol, 2-(diethylamino)- (8CI, 9CI)
MKS
N,N-Diethyl-2-aminoethanol
N,N-Diethyl-2-hydroxyethylamine
N,N-Diethyl-N-(.beta.-hydroxyethyl)amine
N,N-Diethylethanolamine
N,N-Diethylmonoethanolamine
N-(2-Hydroxyethyl)diethylamine
Pennad 150



N,N-Diethyl ethanolamine、Diethyl ethanolamine、2-(diethylamino)-Ethanol、2-Diethylaminoethanol、(2-hydroxyethyl)diethylamine、(diethylamino)ethanol、2-(diethylamino)ethanol、2-(diethylamino)ethyl alcohol、2-hydroxytriethylamine、2-n-diethylaminoethanol


N,N-Diethyl ethanolamine、Diethyl ethanolamine、2-(diethylamino)-Ethanol、2-Diethylaminoethanol、(2-hydroxyethyl)diethylamine、(diethylamino)ethanol、2-(diethylamino)ethanol、2-(diethylamino)ethyl alcohol、2-hydroxytriethylamine、2-n-diethylaminoethanol;2,4-D Diethylethanolamine salt;Acetic acid, (2,4-dichlorophenoxy)-, compd. with 2-(diethylamino)ethanol (1:1)


PRODUCT : DI ETHYL ETHANOLAMINE
CAS No.: 100-37-8
Synonyms: DEEA, N’N’Dimethylethanolamin, Dimethylamino-2-ethanol, 2-(Dimethyl)-1-Ethanol, 2-(imethylamino)ethanol
Formula: C6H15NO
Molecular Weight: 117.19

CAS Numbers:
100-37-8
EC/List Numbers:
202-845-2
Technical Names:
Diethyl Ethanolamine (INCI)
Diethylaminoethanol
Ethanol, 2-(Diethylamino)-
N,N-Diethylethanolamine
Product Categories:
Cleaning Products
Industrial and Automotive Chemicals
Polishes and Floor Maintenance Products
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